Class switch recombination and somatic hypermutation in early mouse B cells are mediated by B cell- and Toll-like receptors.

par Han, Jin-Hwan, Akira, Shizuo, Calame, Kathryn, Beutler, Bruce, Selsing, Erik, Imanishi-Kari, Thereza
Publié 2007

In a SLE mouse model the production of IgG autoantibody requires expression of activation-induced deaminase in early developing B cells

par Umiker, Benjamin R., McDonald, Gabrielle, Larbi, Amma, Medina, Carlos O., Reth, Michael, Imanishi-Kari, Thereza
Publié 2014

Expression of an anti-RNA autoantibody in a mouse model of SLE is sufficient to increase neutrophil and monocyte numbers as well as the amount of IFN-I

par Han, Jin-Hwan, Umiker, Benjamin R., Kazimirova, Anastasia A., Fray, Michael, Korgaonkar, Parimal, Selsing, Erik, Imanishi-Kari, Thereza
Publié 2013

Accelerated Systemic Autoimmunity in the Absence of Somatic Hypermutation in 564Igi: A Mouse Model of Systemic Lupus with Knocked-In Heavy and Light Chain Genes

par McDonald, Gabrielle, Medina, Carlos O., Pilichowska, Monika, Kearney, John F., Shinkura, Reiko, Selsing, Erik, Wortis, Henry H., Honjo, Tasuku, Imanishi-Kari, Thereza
Publié dans Front Immunol (2017)

Dosage of X-linked Toll-like Receptor 8 determines gender differences in the development of systemic lupus erythematosus

par Umiker, Benjamin R., Andersson, Shauna, Fernandez, Luis, Korgaokar, Parimal, Larbi, Amma, Pilichowska, Monika, Weinkauf, Craig C., Wortis, Henry H., Kearney, John, Imanishi-Kari, Thereza
Publié 2014

Female Bias in Systemic Lupus Erythematosus is Associated with the Differential Expression of X-Linked Toll-Like Receptor 8

par McDonald, Gabrielle, Cabal, Nicholas, Vannier, Augustin, Umiker, Benjamin, Yin, Raymund H., Orjalo, Arturo V., Johansson, Hans E., Han, Jin-Hwan, Imanishi-Kari, Thereza
Publié dans Front Immunol (2015)

Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells

par Giltiay, Natalia V., Chappell, Craig P., Sun, Xizhang, Kolhatkar, Nikita, Teal, Thomas H., Wiedeman, Alice E., Kim, Jinoh, Tanaka, Lena, Buechler, Matthew B., Hamerman, Jessica A., Imanishi-Kari, Thereza, Clark, Edward A., Elkon, Keith B.
Publié 2013