AT7867 is a potent and oral inhibitor of AKT and p70 S6 kinase that induces pharmacodynamic changes and inhibits human tumor xenograft growth

Por Grimshaw, Kyla M, Hunter, Lisa-Jane K, Yap, Timothy A, Heaton, Simon, Walton, Mike I, Woodhead, Steve, Fazal, Lynsey, Reule, Matthias, Davies, Thomas G., Seavers, Lisa C., Lock, Victoria, Lyons, John F., Thompson, Neil T., Workman, Paul, Garrett, Michelle D.
Publicado no Mol Cancer Ther (2010)

Preclinical pharmacology, antitumor activity and development of pharmacodynamic markers for the novel, potent AKT inhibitor CCT128930

Por Yap, Timothy A., Walton, Mike I., Hunter, Lisa-Jane K., Valenti, Melanie, de Haven Brandon, Alexis, Eve, Paul D., Ruddle, Ruth, Heaton, Simon P., Henley, Alan, Pickard, Lisa, Vijayaraghavan, Gowri, Caldwell, John J., Thompson, Neil T., Aherne, Wynne, Raynaud, Florence I., Eccles, Suzanne A., Workman, Paul, Collins, Ian, Garrett, Michelle D.
Publicado no Mol Cancer Ther (2010)