Screening of the Pathogen Box reveals new starting points for anti-trypanosomal drug discovery

Por Veale, Clinton G. L., Hoppe, Heinrich C.
Publicado no Medchemcomm (2018)

Differential Effects of Quinoline Antimalarials on Endocytosis in Plasmodium falciparum

Por Roberts, Lindi, Egan, Timothy J., Joiner, Keith A., Hoppe, Heinrich C.
Publicado em 2008

Identification of Novel Potential Inhibitors of Pteridine Reductase 1 in Trypanosoma brucei via Computational Structure-Based Approaches and in Vitro Inhibition Assays

Por Kimuda, Magambo Phillip, Laming, Dustin, Hoppe, Heinrich C., Tastan Bishop, Özlem
Publicado no Molecules (2019)

PfPI3K, a phosphatidylinositol-3 kinase from Plasmodium falciparum, is exported to the host erythrocyte and is involved in hemoglobin trafficking

Por Vaid, Ankush, Ranjan, Ravikant, Smythe, Wynand A., Hoppe, Heinrich C., Sharma, Pushkar
Publicado em 2010

ATP and luciferase assays to determine the rate of drug action in in vitro cultures of Plasmodium falciparum

Por Khan, Tasmiyah, van Brummelen, Anna C, Parkinson, Christopher J, Hoppe, Heinrich C
Publicado em 2012

Evaluation of novel N′-(3-hydroxybenzoyl)-2-oxo-2H-chromene-3-carbohydrazide derivatives as potential HIV-1 integrase inhibitors

Por Jesumoroti, Omobolanle J., Faridoon, Mnkandhla, Dumisani, Isaacs, Michelle, Hoppe, Heinrich C., Klein, Rosalyn
Publicado no Medchemcomm (2018)

Genomes2Drugs: Identifies Target Proteins and Lead Drugs from Proteome Data

Por Toomey, David, Hoppe, Heinrich C., Brennan, Marian P., Nolan, Kevin B., Chubb, Anthony J.
Publicado em 2009

Anti-Trypanosomal and Antimalarial Properties of Tetralone Derivatives and Structurally Related Benzocycloalkanones

Por Beteck, Richard M., Legoabe, Lesetja J., Isaacs, Michelle, Khanye, Setshaba D., Laming, Dustin, Hoppe, Heinrich C.
Publicado no Medicina (Kaunas) (2019)

New Quinolone-Based Thiosemicarbazones Showing Activity Against Plasmodium falciparum and Mycobacterium tuberculosis

Por Beteck, Richard M., Seldon, Ronnett, Jordaan, Audrey, Warner, Digby F., Hoppe, Heinrich C., Laming, Dustin, Khanye, Setshaba D.
Publicado no Molecules (2019)

Antimalarial Quinolines and Artemisinin Inhibit Endocytosis in Plasmodium falciparum

Por Hoppe, Heinrich C., van Schalkwyk, Donelly A., Wiehart, Ursula I. M., Meredith, Sandra A., Egan, Joanne, Weber, Brandon W.
Publicado em 2004

Isolation, Chemical Profile and Antimalarial Activities of Bioactive Compounds from Rauvolfia caffra Sond

Por Tlhapi, Dorcas B., Ramaite, Isaiah D. I., Van Ree, Teunis, Anokwuru, Chinedu P., Orazio, Taglialatela-Scafati, Hoppe, Heinrich C.
Publicado no Molecules (2018)

Quinolone-isoniazid hybrids: synthesis and preliminary in vitro cytotoxicity and anti-tuberculosis evaluation

Por Beteck, Richard M., Seldon, Ronnett, Jordaan, Audrey, Warner, Digby F., Hoppe, Heinrich C., Laming, Dustin, Legoabe, Lesetja J., Khanye, Setshaba D.
Publicado no Medchemcomm (2019)

Insights into the Role of Heme in the Mechanism of Action of Antimalarials

Por Combrinck, Jill M., Mabotha, Tebogo E., Ncokazi, Kanyile K., Ambele, Melvin A., Taylor, Dale, Smith, Peter J., Hoppe, Heinrich C., Egan, Timothy J.
Publicado em 2012

Heterologous expression of plasmodial proteins for structural studies and functional annotation

Por Oldfield Lyndon, Ngcete Zoleka, Morris Elizabeth J, Human Esmaré, Hoppe Heinrich C, Coetzer Theresa L, Blatch Gregory, Birkholtz Lyn-Marie, Roth Robyn, Shonhai Addmore, Stephens Linda, Louw Abraham I
Publicado em 2008-10-01

Heterologous expression of plasmodial proteins for structural studies and functional annotation

Por Birkholtz, Lyn-Marie, Blatch, Gregory, Coetzer, Theresa L, Hoppe, Heinrich C, Human, Esmaré, Morris, Elizabeth J, Ngcete, Zoleka, Oldfield, Lyndon, Roth, Robyn, Shonhai, Addmore, Stephens, Linda, Louw, Abraham I
Publicado em 2008

Plasmodium falciparum encodes a single cytosolic type I Hsp40 that functionally interacts with Hsp70 and is upregulated by heat shock

Por Botha, Melissa, Chiang, Annette N., Needham, Patrick G., Stephens, Linda L., Hoppe, Heinrich C., Külzer, Simone, Przyborski, Jude M., Lingelbach, Klaus, Wipf, Peter, Brodsky, Jeffrey L., Shonhai, Addmore, Blatch, Gregory L.
Publicado em 2010

Biological activities of plant extracts from Ficus elastica and Selaginella vogelli: An antimalarial, antitrypanosomal and cytotoxity evaluation

Por Mbosso Teinkela, Jean Emmanuel, Siwe Noundou, Xavier, Nguemfo, Edwige Laure, Meyer, Franck, Wintjens, Rene, Isaacs, Michelle, Mpondo Mpondo, Albert Emmanuel, Hoppe, Heinrich C., Krause, Rui Werner Maçedo, Azebaze, Anatole Guy Blaise
Publicado no Saudi J Biol Sci (2018)

Cinnamoyl-Oxaborole Amides: Synthesis and Their in Vitro Biological Activity

Por Gumbo, Maureen, Beteck, Richard M., Mandizvo, Tawanda, Seldon, Ronnett, Warner, Digby F., Hoppe, Heinrich C., Isaacs, Michelle, Laming, Dustin, Tam, Christina C., Cheng, Luisa W., Liu, Nicole, Land, Kirkwood M., Khanye, Setshaba D.
Publicado no Molecules (2018)