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ATP and luciferase assays to determine the rate of drug action in in vitro cultures of Plasmodium falciparum

BACKGROUND: Knowledge of the rate of action of compounds against cultured malaria parasites is required to determine the optimal time-points for drug mode of action studies, as well as to predict likely in vivo parasite clearance rates in order to select optimal hit compounds for further development...

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Sonraí Bibleagrafaíochta
Main Authors: Khan, Tasmiyah, van Brummelen, Anna C, Parkinson, Christopher J, Hoppe, Heinrich C
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505462/
https://ncbi.nlm.nih.gov/pubmed/23134617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-369
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