Medicinal chemistry for 2020

por Satyanarayanajois, Seetharama D, Hill, Ronald A
Publicado 2011

Small ceramide tames big p53 mutant beast

por Hill, Ronald A., Liu, Zhijun, Liu, Yong-Yu
Publicado en Oncotarget (2020)

Mass Psychogenic Illness: Psychological Predisposition and Iatrogenic Pseudo-vocal Cord Dysfunction and Pseudo-reactive Airways Disease Syndrome

por Staudenmayer, Herman, Christopher, Kent L., Repsher, Lawrence, Hill, Ronald H.
Publicado 2011

Enhanced Brain Amyloid-β Clearance by Rifampicin and Caffeine as a Possible Protective Mechanism Against Alzheimer’s Disease

por Qosa, Hisham, Abuznait, Alaa H., Hill, Ronald A., Kaddoumi, Amal
Publicado 2012

Genetic Evidence for Function of the bHLH-PAS Protein Gce/Met As a Juvenile Hormone Receptor

por Jindra, Marek, Uhlirova, Mirka, Charles, Jean-Philippe, Smykal, Vlastimil, Hill, Ronald J.
Publicado en PLoS Genet (2015)

Transporters as Drug Targets in Neurological Diseases

por Qosa, Hisham, Mohamed, Loqman A., Alqahtani, Saeed, Abuasal, Bilal S., Hill, Ronald A., Kaddoumi, Amal
Publicado en Clin Pharmacol Ther (2016)

Estimation of Postoperative Fluid Requirements in Infants and Children

por Filston, Howard C., Edwards, Charles H., Chitwood, W. Randolph, Larson, Richard M., Marsicano, Thomas H., Hill, Ronald C.
Publicado 1982

(−)-Oleocanthal Prevents Breast Cancer Locoregional Recurrence After Primary Tumor Surgical Excision and Neoadjuvant Targeted Therapy in Orthotopic Nude Mouse Models

por Siddique, Abu Bakar, Ayoub, Nehad M., Tajmim, Afsana, Meyer, Sharon A., Hill, Ronald A., El Sayed, Khalid A.
Publicado en Cancers (Basel) (2019)

Saphenous vein graft failure and clinical outcomes: Toward a surrogate end point in patients following coronary artery bypass surgery?

por Harskamp, Ralf E., Williams, Judson B., Hill, Ronald C., de Winter, Robbert J., Alexander, John H., Lopes, Renato D.
Publicado 2013

In vitro injection of osteoporotic cadaveric femurs with a triphasic calcium‐based implant confers immediate biomechanical integrity

por Stroncek, John D., Shaul, Jonathan L., Favell, Dominique, Hill, Ronald S., Huber, Bryan M., Howe, James G., Bouxsein, Mary L.
Publicado en J Orthop Res (2019)

Identification of the major human hepatic and placental enzymes responsible for the biotransformation of glyburide

por Zharikova, Olga L., Fokina, Valentina M., Nanovskaya, Tatiana N., Hill, Ronald A., Mattison, Donald R., Hankins, Gary D.V., Ahmed, Mahmoud S.
Publicado 2009

Incorporation of Fluorescence Ceramide-Based HPLC Assay for Rapidly and Efficiently Assessing Glucosylceramide Synthase In Vivo

por Khiste, Sachin K., Hosain, Salman B., Dong, Yixuan, Uddin, Mohammad B., Roy, Kartik R., Hill, Ronald A., Liu, Zhijun, Liu, Yong-Yu
Publicado en Sci Rep (2017)

Inhibition of glucosylceramide synthase eliminates the oncogenic function of p53 R273H mutant in the epithelial-mesenchymal transition and induced pluripotency of colon cancer cell...

por Hosain, Salman B., Khiste, Sachin K., Uddin, Mohammad B., Vorubindi, Vindya, Ingram, Catherine, Zhang, Sifang, Hill, Ronald A., Gu, Xin, Liu, Yong-Yu
Publicado en Oncotarget (2016)

Ceramide-Rubusoside Nanomicelles, a Potential Therapeutic Approach to Target Cancers Carrying p53 Missense Mutations

por Khiste, Sachin K., Liu, Zhijun, Roy, Kartik R., Uddin, Mohammad B., Hosain, Salman B., Gu, Xin, Nazzal, Sami, Hill, Ronald A., Liu, Yong-Yu
Publicado en Mol Cancer Ther (2019)

Gb3‐cSrc complex in glycosphingolipid‐enriched microdomains contributes to the expression of p53 mutant protein and cancer drug resistance via β‐catenin–activated RNA methylation...

por Roy, Kartik R., Uddin, Mohammad B., Roy, Sagor C., Hill, Ronald A., Marshall, John, Li, Yu‐Teh, Chamcheu, Jean Christopher, Lu, Hua, Liu, Yong‐Yu
Publicado en FASEB Bioadv (2020)

A Small Molecule Inhibitor of ITK and RLK Impairs Th1 Differentiation and Prevents Colitis Disease Progression

por Cho, Hyoung-Soo, Shin, Hyun Mu, Haberstock-Debic, Helena, Xing, Yan, Owens, Timothy D., Funk, Jens Oliver, Hill, Ronald J., Bradshaw, J. Michael, Berg, Leslie J.
Publicado en J Immunol (2015)

PRN473, an inhibitor of Bruton's tyrosine kinase, inhibits neutrophil recruitment via inhibition of macrophage antigen‐1 signalling

por Herter, Jan M, Margraf, Andreas, Volmering, Stephanie, Correia, Benedito Eduardo, Bradshaw, J Michael, Bisconte, Angelina, Hill, Ronald J, Langrish, Claire L, Lowell, Clifford A, Zarbock, Alexander
Publicado en Br J Pharmacol (2017)

An N(6)-methyladenosine at the transited codon 273 of p53 pre-mRNA promotes the expression of R273H mutant protein and drug resistance of cancer cells

por Uddin, Mohammad B., Roy, Kartik R., Hosain, Salman B., Khiste, Sachin K., Hill, Ronald A., Jois, Seetharama D., Zhao, Yunfeng, Tackett, Alan J., Liu, Yong-Yu
Publicado en Biochem Pharmacol (2018)

Preclinical Efficacy and Anti-Inflammatory Mechanisms of Action of the Bruton Tyrosine Kinase Inhibitor Rilzabrutinib for Immune-Mediated Disease

por Langrish, Claire L., Bradshaw, J. Michael, Francesco, Michelle R., Owens, Timothy D., Xing, Yan, Shu, Jin, LaStant, Jacob, Bisconte, Angelina, Outerbridge, Catherine, White, Stephen D., Hill, Ronald J., Brameld, Ken A., Goldstein, David M., Nunn, Philip A.
Publicado en J Immunol (2021)

Targeting Interleukin-2-inducible T-cell Kinase (ITK) and Resting Lymphocyte Kinase (RLK) Using a Novel Covalent Inhibitor PRN694

por Zhong, Yiming, Dong, Shuai, Strattan, Ethan, Ren, Li, Butchar, Jonathan P., Thornton, Kelsey, Mishra, Anjali, Porcu, Pierluigi, Bradshaw, J. Michael, Bisconte, Angelina, Owens, Timothy D., Verner, Erik, Brameld, Ken A., Funk, Jens Oliver, Hill, Ronald J., Johnson, Amy J., Dubovsky, Jason A.
Publicado en J Biol Chem (2015)