Ceramide-Rubusoside Nanomicelles, a Potential Therapeutic Approach to Target Cancers Carrying p53 Missense Mutations

Ceramide (Cer) is an active cellular sphingolipid that can induce apoptosis or proliferation-arrest of cancer cells. Nanoparticle-based delivery offers an effective approach for overcoming bioavailability and biopharmaceutics issues attributable to the pronounced hydrophobicity of Cer. Missense muta...

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Detalhes bibliográficos
Publicado no:Mol Cancer Ther
Main Authors: Khiste, Sachin K., Liu, Zhijun, Roy, Kartik R., Uddin, Mohammad B., Hosain, Salman B., Gu, Xin, Nazzal, Sami, Hill, Ronald A., Liu, Yong-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7007850/
https://ncbi.nlm.nih.gov/pubmed/31645443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-19-0366
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