Using genomics to better define high-risk MGUS/SMM patients

gan Dutta, Ankit K., Hewett, Duncan R., Fink, J. Lynn, Zannettino, Andrew C.W.
Cyhoeddwyd yn Oncotarget (2018)

SAMSN1 Is a Tumor Suppressor Gene in Multiple Myeloma()()

gan Noll, Jacqueline E., Hewett, Duncan R., Williams, Sharon A., Vandyke, Kate, Kok, Chung, To, Luen B., Zannettino, Andrew C.W.
Cyhoeddwyd 2014

GLIPR1 expression is reduced in multiple myeloma but is not a tumour suppressor in mice

gan Friend, Natasha, Noll, Jacqueline E., Opperman, Khatora S., Clark, Kimberley C., Mrozik, Krzysztof M., Vandyke, Kate, Hewett, Duncan R., Zannettino, Andrew C. W.
Cyhoeddwyd yn PLoS One (2020)

Characterization of the role of Samsn1 loss in multiple myeloma development

gan Friend, Natasha L., Hewett, Duncan R., Panagopoulos, Vasilios, Noll, Jacqueline E., Vandyke, Kate, Mrozik, Krzysztof M., Fitter, Stephen, Zannettino, Andrew C.W.
Cyhoeddwyd yn FASEB Bioadv (2020)

PTTG1 expression is associated with hyperproliferative disease and poor prognosis in multiple myeloma

gan Noll, Jacqueline E., Vandyke, Kate, Hewett, Duncan R., Mrozik, Krzysztof M., Bala, Rachel J., Williams, Sharon A., Kok, Chung H., Zannettino, Andrew CW
Cyhoeddwyd yn J Hematol Oncol (2015)

DNA Barcoding Reveals Habitual Clonal Dominance of Myeloma Plasma Cells in the Bone Marrow Microenvironment

gan Hewett, Duncan R., Vandyke, Kate, Lawrence, David M., Friend, Natasha, Noll, Jacqueline E., Geoghegan, Joel M., Croucher, Peter I., Zannettino, Andrew C.W.
Cyhoeddwyd yn Neoplasia (2017)

Subclonal evolution in disease progression from MGUS/SMM to multiple myeloma is characterised by clonal stability

gan Dutta, Ankit K., Fink, J. Lynn, Grady, John P., Morgan, Gareth J., Mullighan, Charles G., To, Luen B., Hewett, Duncan R., Zannettino, Andrew C. W.
Cyhoeddwyd yn Leukemia (2018)

Twist-1 is upregulated by NSD2 and contributes to tumour dissemination and an epithelial-mesenchymal transition-like gene expression signature in t(4;14)-positive multiple myeloma

gan Cheong, Chee Man, Mrozik, Krzysztof M., Hewett, Duncan R., Bell, Elyse, Panagopoulos, Vasilios, Noll, Jacqueline E., Licht, Jonathan D., Gronthos, Stan, Zannettino, Andrew C.W., Vandyke, Kate
Cyhoeddwyd yn Cancer Lett (2020)

Identification of an interleukin (IL)-25–dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion

gan Fallon, Padraic G., Ballantyne, Sarah J., Mangan, Niamh E., Barlow, Jillian L., Dasvarma, Ayan, Hewett, Duncan R., McIlgorm, Ann, Jolin, Helen E., McKenzie, Andrew N.J.
Cyhoeddwyd 2006

LCRF‐0006, a small molecule mimetic of the N‐cadherin antagonist peptide ADH‐1, synergistically increases multiple myeloma response to bortezomib

gan Mrozik, Krzysztof M., Cheong, Chee M., Hewett, Duncan R., Noll, Jacqueline E., Opperman, Khatora S., Adwal, Alaknanda, Russell, Darryl L., Blaschuk, Orest W., Vandyke, Kate, Zannettino, Andrew C. W.
Cyhoeddwyd yn FASEB Bioadv (2020)

Sphingosine kinase 2 inhibition synergises with bortezomib to target myeloma by enhancing endoplasmic reticulum stress

gan Wallington-Beddoe, Craig T., Bennett, Melissa K., Vandyke, Kate, Davies, Lorena, Zebol, Julia R., Moretti, Paul A.B., Pitman, Melissa R., Hewett, Duncan R., Zannettino, Andrew C.W., Pitson, Stuart M
Cyhoeddwyd yn Oncotarget (2017)

Clodronate-Liposome Mediated Macrophage Depletion Abrogates Multiple Myeloma Tumor Establishment In Vivo

gan Opperman, Khatora S., Vandyke, Kate, Clark, Kimberley C., Coulter, Elizabeth A., Hewett, Duncan R., Mrozik, Krzysztof M., Schwarz, Nisha, Evdokiou, Andreas, Croucher, Peter I, Psaltis, Peter J, Noll, Jacqueline E, Zannettino, Andrew CW
Cyhoeddwyd yn Neoplasia (2019)

Targeted Disruption of Bone Marrow Stromal Cell-Derived Gremlin1 Limits Multiple Myeloma Disease Progression In Vivo

gan Clark, Kimberley C., Hewett, Duncan R., Panagopoulos, Vasilios, Plakhova, Natalya, Opperman, Khatora S., Bradey, Alanah L., Mrozik, Krzysztof M., Vandyke, Kate, Mukherjee, Siddhartha, Davies, Gareth C.G., Worthley, Daniel L., Zannettino, Andrew C.W.
Cyhoeddwyd yn Cancers (Basel) (2020)

A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q(−) syndrome

gan Barlow, Jillian L., Drynan, Lesley F., Hewett, Duncan R., Holmes, Luke R., Lorenzo-Abalde, Silvia, Lane, Alison L., Jolin, Helen E., Pannell, Richard, Middleton, Angela J., Wong, See Heng, Warren, Alan J, Wainscoat, James S., Boultwood, Jacqueline, McKenzie, Andrew N.J.
Cyhoeddwyd 2009