Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine‐based inhibitor co‐crystal structure

le Marcotte, Douglas J., Hus, Jean‐Christophe, Banos, Charles C., Wildes, Craig, Arduini, Robert, Bergeron, Chris, Hession, Catherine A., Baker, Darren P., Lin, Edward, Guckian, Kevin M., Dunah, Anthone W., Silvian, Laura F.
Foilsithe in Protein Sci (2018)

Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases

le Marcotte, Douglas J, Liu, Yu-Ting, Arduini, Robert M, Hession, Catherine A, Miatkowski, Konrad, Wildes, Craig P, Cullen, Patrick F, Hong, Victor, Hopkins, Brian T, Mertsching, Elisabeth, Jenkins, Tracy J, Romanowski, Michael J, Baker, Darren P, Silvian, Laura F
Foilsithe 2010

Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction

le Lin, Edward Y. S., Silvian, Laura F., Marcotte, Douglas J., Banos, Charles C., Jow, Flora, Chan, Timothy R., Arduini, Robert M., Qian, Fang, Baker, Darren P., Bergeron, Chris, Hession, Catherine A., Huganir, Richard L., Borenstein, Cassandra F., Enyedy, Istvan, Zou, Jinming, Rohde, Ellen, Wittmann, Marion, Kumaravel, Gnanasambandam, Rhodes, Kenneth J., Scannevin, Robert H., Dunah, Anthone W., Guckian, Kevin M.
Foilsithe in Sci Rep (2018)