Tetrahydroisoquinoline CXCR4 Antagonists Adopt a Hybrid Binding Mode within the Peptide Subpocket of the CXCR4 Receptor

od Katzman, Brooke M., Cox, Bryan D., Prosser, Anthony R., Alcaraz, Ana A., Murat, Brigitte, Héroux, Madeleine, Tebben, Andrew, Zhang, Yong, Schroeder, Gretchen M., Snyder, James P., Wilson, Lawrence J., Liotta, Dennis C.
Wydane w ACS Med Chem Lett (2018)

In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure

od Gargalovic, Peter, Wong, Pancras, Onorato, Joelle, Finlay, Heather, Wang, Tao, Yan, Mujing, Crain, Earl, St-Onge, Stéphane, Héroux, Madeleine, Bouvier, Michel, Xu, Carrie, Chen, Xue-Qing, Generaux, Claudia, Lawrence, Michael, Wexler, Ruth, Gordon, David
Wydane w Circ Heart Fail (2021)

BRET-based effector membrane translocation assay monitors GPCR-promoted and endocytosis-mediated G(q) activation at early endosomes

od Wright, Shane C., Lukasheva, Viktoriya, Le Gouill, Christian, Kobayashi, Hiroyuki, Breton, Billy, Mailhot-Larouche, Samuel, Blondel-Tepaz, Élodie, Antunes Vieira, Nichelle, Costa-Neto, Claudio, Héroux, Madeleine, Lambert, Nevin A., Parreiras-e-Silva, Lucas Tabajara, Bouvier, Michel
Wydane w Proc Natl Acad Sci U S A (2021)

Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells

od Volpi, Claudia, Mondanelli, Giada, Pallotta, Maria T., Vacca, Carmine, Iacono, Alberta, Gargaro, Marco, Albini, Elisa, Bianchi, Roberta, Belladonna, Maria L., Celanire, Sylvain, Mordant, Céline, Heroux, Madeleine, Royer-Urios, Isabelle, Schneider, Manfred, Vitte, Pierre-Alain, Cacquevel, Mathias, Galibert, Laurent, Poli, Sonia-Maria, Solari, Aldo, Bicciato, Silvio, Calvitti, Mario, Antognelli, Cinzia, Puccetti, Paolo, Orabona, Ciriana, Fallarino, Francesca, Grohmann, Ursula
Wydane w Neuropharmacology (2016)

Preservation of Post-Infarction Cardiac Structure and Function via Long-Term Oral Formyl Peptide Receptor Agonist Treatment

od García, Ricardo A., Ito, Bruce R., Lupisella, John A., Carson, Nancy A., Hsu, Mei-Yin, Fernando, Gayani, Heroux, Madeleine, Bouvier, Michel, Dierks, Elizabeth, Kick, Ellen K., Gordon, David A., Chen, Jian, Mintier, Gabe, Carrier, Marilyn, St-Onge, Stéphane, Shah, Himanshu, Towne, Jordan, Bucardo, Marcela Sotelo, Ma, Xiuying, Ryan, Carol S., Wurtz, Nicholas R., Ostrowski, Jacek, Villarreal, Francisco J.
Wydane w JACC Basic Transl Sci (2019)