Tetrahydroisoquinoline CXCR4 Antagonists Adopt a Hybrid Binding Mode within the Peptide Subpocket of the CXCR4 Receptor

Por Katzman, Brooke M., Cox, Bryan D., Prosser, Anthony R., Alcaraz, Ana A., Murat, Brigitte, Héroux, Madeleine, Tebben, Andrew, Zhang, Yong, Schroeder, Gretchen M., Snyder, James P., Wilson, Lawrence J., Liotta, Dennis C.
Publicado no ACS Med Chem Lett (2018)

In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure

Por Gargalovic, Peter, Wong, Pancras, Onorato, Joelle, Finlay, Heather, Wang, Tao, Yan, Mujing, Crain, Earl, St-Onge, Stéphane, Héroux, Madeleine, Bouvier, Michel, Xu, Carrie, Chen, Xue-Qing, Generaux, Claudia, Lawrence, Michael, Wexler, Ruth, Gordon, David
Publicado no Circ Heart Fail (2021)

Allosteric modulation of metabotropic glutamate receptor 4 activates IDO1-dependent, immunoregulatory signaling in dendritic cells

Por Volpi, Claudia, Mondanelli, Giada, Pallotta, Maria T., Vacca, Carmine, Iacono, Alberta, Gargaro, Marco, Albini, Elisa, Bianchi, Roberta, Belladonna, Maria L., Celanire, Sylvain, Mordant, Céline, Heroux, Madeleine, Royer-Urios, Isabelle, Schneider, Manfred, Vitte, Pierre-Alain, Cacquevel, Mathias, Galibert, Laurent, Poli, Sonia-Maria, Solari, Aldo, Bicciato, Silvio, Calvitti, Mario, Antognelli, Cinzia, Puccetti, Paolo, Orabona, Ciriana, Fallarino, Francesca, Grohmann, Ursula
Publicado no Neuropharmacology (2016)

Preservation of Post-Infarction Cardiac Structure and Function via Long-Term Oral Formyl Peptide Receptor Agonist Treatment

Por García, Ricardo A., Ito, Bruce R., Lupisella, John A., Carson, Nancy A., Hsu, Mei-Yin, Fernando, Gayani, Heroux, Madeleine, Bouvier, Michel, Dierks, Elizabeth, Kick, Ellen K., Gordon, David A., Chen, Jian, Mintier, Gabe, Carrier, Marilyn, St-Onge, Stéphane, Shah, Himanshu, Towne, Jordan, Bucardo, Marcela Sotelo, Ma, Xiuying, Ryan, Carol S., Wurtz, Nicholas R., Ostrowski, Jacek, Villarreal, Francisco J.
Publicado no JACC Basic Transl Sci (2019)