An integrated structure- and system-based framework to identify new targets of metabolites and known drugs

von Naveed, Hammad, Hameed, Umar S., Harrus, Deborah, Bourguet, William, Arold, Stefan T., Gao, Xin
Veröffentlicht in Bioinformatics (2015)

Two Crucial Early Steps in RNA Synthesis by the Hepatitis C Virus Polymerase Involve a Dual Role of Residue 405

von Scrima, Nathalie, Caillet-Saguy, Célia, Ventura, Michel, Harrus, Déborah, Astier-Gin, Thérèse, Bressanelli, Stéphane
Veröffentlicht 2012

Abnormal Golgi pH Homeostasis in Cancer Cells Impairs Apical Targeting of Carcinoembryonic Antigen by Inhibiting Its Glycosyl-Phosphatidylinositol Anchor-Mediated Association with...

von Kokkonen, Nina, Khosrowabadi, Elham, Hassinen, Antti, Harrus, Deborah, Glumoff, Tuomo, Kietzmann, Thomas, Kellokumpu, Sakari
Veröffentlicht in Antioxid Redox Signal (2019)

The dimeric structure of wild-type human glycosyltransferase B4GalT1

von Harrus, Deborah, Khoder-Agha, Fawzi, Peltoniemi, Miika, Hassinen, Antti, Ruddock, Lloyd, Kellokumpu, Sakari, Glumoff, Tuomo
Veröffentlicht in PLoS One (2018)

Assembly of B4GALT1/ST6GAL1 heteromers in the Golgi membranes involves lateral interactions via highly charged surface domains

von Khoder-Agha, Fawzi, Harrus, Deborah, Brysbaert, Guillaume, Lensink, Marc F., Harduin-Lepers, Anne, Glumoff, Tuomo, Kellokumpu, Sakari
Veröffentlicht in J Biol Chem (2019)

Molecular mechanisms of transcriptional control by Rev-erbα: An energetic foundation for reconciling structure and binding with biological function

von Vaissière, Anaïs, Berger, Sylvie, Harrus, Deborah, Dacquet, Catherine, Le Maire, Albane, Boutin, Jean A, Ferry, Gilles, Royer, Catherine A
Veröffentlicht in Protein Sci (2015)

A Golgi-associated redox switch regulates catalytic activation and cooperative functioning of ST6Gal-I with B4GalT-I

von Hassinen, Antti, Khoder-Agha, Fawzi, Khosrowabadi, Elham, Mennerich, Daniela, Harrus, Deborah, Noel, Maxence, Dimova, Elitsa Y., Glumoff, Tuomo, Harduin-Lepers, Anne, Kietzmann, Thomas, Kellokumpu, Sakari
Veröffentlicht in Redox Biol (2019)

Further Insights into the Roles of GTP and the C Terminus of the Hepatitis C Virus Polymerase in the Initiation of RNA Synthesis

von Harrus, Déborah, Ahmed-El-Sayed, Neveen, Simister, Philip C., Miller, Steve, Triconnet, Martine, Hagedorn, Curt H., Mahias, Kathleen, Rey, Félix A., Astier-Gin, Thérèse, Bressanelli, Stéphane
Veröffentlicht 2010

Mechanistic insights into the synergistic activation of the RXR–PXR heterodimer by endocrine disruptor mixtures

von Delfosse, Vanessa, Huet, Tiphaine, Harrus, Deborah, Granell, Meritxell, Bourguet, Maxime, Gardia-Parège, Caroline, Chiavarina, Barbara, Grimaldi, Marina, Le Mével, Sébastien, Blanc, Pauline, Huang, David, Gruszczyk, Jakub, Demeneix, Barbara, Cianférani, Sarah, Fini, Jean-Baptiste, Balaguer, Patrick, Bourguet, William
Veröffentlicht in Proc Natl Acad Sci U S A (2021)