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The dimeric structure of wild-type human glycosyltransferase B4GalT1

Most glycosyltransferases, including B4GalT1 (EC 2.4.1.38), are known to assemble into enzyme homomers and functionally relevant heteromers in vivo. However, it remains unclear why and how these enzymes interact at the molecular/atomic level. Here, we solved the crystal structure of the wild-type hu...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Harrus, Deborah, Khoder-Agha, Fawzi, Peltoniemi, Miika, Hassinen, Antti, Ruddock, Lloyd, Kellokumpu, Sakari, Glumoff, Tuomo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198961/
https://ncbi.nlm.nih.gov/pubmed/30352055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205571
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