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An integrated structure- and system-based framework to identify new targets of metabolites and known drugs
Motivation: The inherent promiscuity of small molecules towards protein targets impedes our understanding of healthy versus diseased metabolism. This promiscuity also poses a challenge for the pharmaceutical industry as identifying all protein targets is important to assess (side) effects and reposi...
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4673972/ https://ncbi.nlm.nih.gov/pubmed/26286808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv477 |
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