ToxPoint: In the Era of Precision Medicine, Diversity Should Not Be Neglected in Chemical Safety Assessment

Autor Harrill, Alison H
Vydáno v Toxicol Sci (2020)

Urinary microRNAs in environmental health: biomarkers of emergent kidney injury and disease

Autor Harrill, Alison H., Sanders, Alison
Vydáno v Curr Environ Health Rep (2020)

New Rodent Population Models May Inform Human Health Risk Assessment and Identification of Genetic Susceptibility to Environmental Exposures

Autor Harrill, Alison H., McAllister, Kimberly A.
Vydáno v Environ Health Perspect (2017)

Mouse population-based evaluation of urinary protein and miRNA biomarker performance associated with cisplatin renal injury

Autor Harrill, Alison H, Lin, Haixia, Tobacyk, Julia, Seely, John C
Vydáno v Exp Biol Med (Maywood) (2017)

Population-Based Discovery of Toxicogenomics Biomarkers for Hepatotoxicity Using a Laboratory Strain Diversity Panel

Autor Harrill, Alison H., Ross, Pamela K., Gatti, Daniel M., Threadgill, David W., Rusyn, Ivan
Vydáno 2009

Replication and Narrowing of Gene Expression Quantitative Trait Loci using Inbred Mice

Autor Gatti, Daniel M., Harrill, Alison H., Wright, Fred A., Threadgill, David W., Rusyn, Ivan
Vydáno 2009

Benign elevations in serum aminotransferases and biomarkers of hepatotoxicity in healthy volunteers treated with cholestyramine

Autor Singhal, Rohit, Harrill, Alison H, Menguy-Vacheron, Francoise, Jayyosi, Zaid, Benzerdjeb, Hadj, Watkins, Paul B
Vydáno 2014

RATEmiRs: the rat atlas of tissue-specific and enriched miRNAs for discerning baseline expression exclusivity of candidate biomarkers

Autor Bushel, Pierre R., Caiment, Florian, Wu, Han, O’Lone, Raegan, Day, Frank, Calley, John, Smith, Aaron, Li, Jianying, Harrill, Alison H.
Vydáno v RNA Biol (2020)

A cross-sector call to improve carcinogenicity risk assessment through use of genomic methodologies

Autor Yauk, Carole L., Harrill, Alison H., Ellinger-Ziegelbauer, Heidrun, van der Laan, Jan Willem, Moggs, Jonathan, Froetschl, Roland, Sistare, Frank, Pettit, Syril
Vydáno v Regul Toxicol Pharmacol (2019)

Beyond miR-122: Identification of MicroRNA Alterations in Blood During a Time Course of Hepatobiliary Injury and Biliary Hyperplasia in Rats

Autor Church, Rachel J., Otieno, Monicah, McDuffie, James Eric, Singh, Bhanu, Sonee, Manisha, Hall, LeRoy, Watkins, Paul B., Ellinger-Ziegelbauer, Heidrun, Harrill, Alison H.
Vydáno v Toxicol Sci (2016)

Nitrosative Stress and Lipid Homeostasis as a Mechanism for Zileuton Hepatotoxicity and Resistance in Genetically Sensitive Mice

Autor You, Dahea, Lyn-Cook, Lascelles E, Gatti, Daniel M, Bell, Natalie, Mayeux, Philip R, James, Laura P, Mattes, William B, Larson, Gary J, Harrill, Alison H
Vydáno v Toxicol Sci (2020)

A Mouse Diversity Panel Approach Reveals the Potential for Clinical Kidney Injury Due to DB289 Not Predicted by Classical Rodent Models

Autor Harrill, Alison H., DeSmet, Kristina D., Wolf, Kristina K., Bridges, Arlene S., Eaddy, J. Scott, Kurtz, C. Lisa, Hall, J. Ed., Paine, Mary F., Tidwell, Richard R., Watkins, Paul B.
Vydáno 2012

A Systems Biology Approach Utilizing a Mouse Diversity Panel Identifies Genetic Differences Influencing Isoniazid-Induced Microvesicular Steatosis

Autor Church, Rachel J., Wu, Hong, Mosedale, Merrie, Sumner, Susan J., Pathmasiri, Wimal, Kurtz, Catherine L., Pletcher, Mathew T., Eaddy, John S., Pandher, Karamjeet, Singer, Monica, Batheja, Ameesha, Watkins, Paul B., Adkins, Karissa, Harrill, Alison H.
Vydáno 2014

Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice

Autor Church, Rachel J., Gatti, Daniel M., Urban, Thomas J., Long, Nanye, Yang, Xi, Shi, Qiang, Eaddy, J. Scott, Mosedale, Merrie, Ballard, Shawn, Churchill, Gary A., Navarro, Victor, Watkins, Paul B., Threadgill, David W., Harrill, Alison H.
Vydáno v Food Chem Toxicol (2014)

Urinary miRNA Biomarkers of Drug-Induced Kidney Injury and Their Site Specificity Within the Nephron

Autor Chorley, Brian N, Ellinger-Ziegelbauer, Heidrun, Tackett, Michael, Simutis, Frank J, Harrill, Alison H, McDuffie, James, Atabakhsh, Elnaz, Nassirpour, Rounak, Whiteley, Laurence O, Léonard, Jean-François, Carswell, Gleta K, Harpur, Ernie, Chen, Connie L, Gautier, Jean-Charles
Vydáno v Toxicol Sci (2020)

Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans

Autor Harrill, Alison H., Watkins, Paul B., Su, Stephen, Ross, Pamela K., Harbourt, David E., Stylianou, Ioannis M., Boorman, Gary A., Russo, Mark W., Sackler, Richard S., Harris, Stephen C., Smith, Philip C., Tennant, Raymond, Bogue, Molly, Paigen, Kenneth, Harris, Christopher, Contractor, Tanupriya, Wiltshire, Timothy, Rusyn, Ivan, Threadgill, David W.
Vydáno 2009

MAPPING THE EFFECTS OF GENETIC VARIATION ON CHROMATIN STATE AND GENE EXPRESSION REVEALS LOCI THAT CONTROL GROUND STATE PLURIPOTENCY

Autor Skelly, Daniel A., Czechanski, Anne, Byers, Candice, Aydin, Selcan, Spruce, Catrina, Olivier, Chris, Choi, Kwangbom, Gatti, Daniel M., Raghupathy, Narayanan, Keele, Gregory R., Stanton, Alexander, Vincent, Matthew, Dion, Stephanie, Greenstein, Ian, Pankratz, Matthew, Porter, Devin K., Martin, Whitney, O’Connor, Callan, Qin, Wenning, Harrill, Alison H., Choi, Ted, Churchill, Gary A., Munger, Steven C., Baker, Christopher L., Reinholdt, Laura G.
Vydáno v Cell Stem Cell (2020)

A Multi-Megabase Copy Number Gain Causes Maternal Transmission Ratio Distortion on Mouse Chromosome 2

Autor Didion, John P., Morgan, Andrew P., Clayshulte, Amelia M.-F., Mcmullan, Rachel C., Yadgary, Liran, Petkov, Petko M., Bell, Timothy A., Gatti, Daniel M., Crowley, James J., Hua, Kunjie, Aylor, David L., Bai, Ling, Calaway, Mark, Chesler, Elissa J., French, John E., Geiger, Thomas R., Gooch, Terry J., Garland, Theodore, Harrill, Alison H., Hunter, Kent, McMillan, Leonard, Holt, Matt, Miller, Darla R., O'Brien, Deborah A., Paigen, Kenneth, Pan, Wenqi, Rowe, Lucy B., Shaw, Ginger D., Simecek, Petr, Sullivan, Patrick F., Svenson, Karen L, Weinstock, George M., Threadgill, David W., Pomp, Daniel, Churchill, Gary A., Pardo-Manuel de Villena, Fernando
Vydáno v PLoS Genet (2015)