Selective deletion of Jak2 in adult mouse hematopoietic cells leads to lethal anemia and thrombocytopenia

由 Grisouard, Jean, Hao-Shen, Hui, Dirnhofer, Stephan, Wagner, Kay-Uwe, Skoda, Radek C.
出版 2014

Myeloproliferative neoplasms can be initiated from a single hematopoietic stem cell expressing JAK2-V617F

由 Lundberg, Pontus, Takizawa, Hitoshi, Kubovcakova, Lucia, Guo, Guoji, Hao-Shen, Hui, Dirnhofer, Stephan, Orkin, Stuart H., Manz, Markus G., Skoda, Radek C.
出版 2014

Loss of Ezh2 synergizes with JAK2-V617F in initiating myeloproliferative neoplasms and promoting myelofibrosis

由 Shimizu, Takafumi, Kubovcakova, Lucia, Nienhold, Ronny, Zmajkovic, Jakub, Meyer, Sara C., Hao-Shen, Hui, Geier, Florian, Dirnhofer, Stephan, Guglielmelli, Paola, Vannucchi, Alessandro M., Feenstra, Jelena D. Milosevic, Kralovics, Robert, Orkin, Stuart H., Skoda, Radek C.
發表在 J Exp Med (2016)

Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms

由 Stivala, Simona, Codilupi, Tamara, Brkic, Sime, Baerenwaldt, Anne, Ghosh, Nilabh, Hao-Shen, Hui, Dirnhofer, Stephan, Dettmer, Matthias S., Simillion, Cedric, Kaufmann, Beat A., Chiu, Sophia, Keller, Matthew, Kleppe, Maria, Hilpert, Morgane, Buser, Andreas S., Passweg, Jakob R., Radimerski, Thomas, Skoda, Radek C., Levine, Ross L., Meyer, Sara C.
發表在 J Clin Invest (2019)

JAK2-mutant hematopoietic cells display metabolic alterations that can be targeted to treat myeloproliferative neoplasms

由 Rao, Tata Nageswara, Hansen, Nils, Hilfiker, Julian, Rai, Shivam, Majewska, Julia-Magdalena, Leković, Danijela, Gezer, Deniz, Andina, Nicola, Galli, Serena, Cassel, Teresa, Geier, Florian, Delezie, Julien, Nienhold, Ronny, Hao-Shen, Hui, Beisel, Christian, Di Palma, Serena, Dimeloe, Sarah, Trebicka, Jonel, Wolf, Dominik, Gassmann, Max, Fan, Teresa W.-M., Lane, Andrew N., Handschin, Christoph, Dirnhofer, Stefan, Kröger, Nicolaus, Hess, Christoph, Radimerski, Thomas, Koschmieder, Steffen, Čokić, Vladan P., Skoda, Radek C.
發表在 Blood (2019)