Selective deletion of Jak2 in adult mouse hematopoietic cells leads to lethal anemia and thrombocytopenia

od Grisouard, Jean, Hao-Shen, Hui, Dirnhofer, Stephan, Wagner, Kay-Uwe, Skoda, Radek C.
Wydane 2014

Myeloproliferative neoplasms can be initiated from a single hematopoietic stem cell expressing JAK2-V617F

od Lundberg, Pontus, Takizawa, Hitoshi, Kubovcakova, Lucia, Guo, Guoji, Hao-Shen, Hui, Dirnhofer, Stephan, Orkin, Stuart H., Manz, Markus G., Skoda, Radek C.
Wydane 2014

Loss of Ezh2 synergizes with JAK2-V617F in initiating myeloproliferative neoplasms and promoting myelofibrosis

od Shimizu, Takafumi, Kubovcakova, Lucia, Nienhold, Ronny, Zmajkovic, Jakub, Meyer, Sara C., Hao-Shen, Hui, Geier, Florian, Dirnhofer, Stephan, Guglielmelli, Paola, Vannucchi, Alessandro M., Feenstra, Jelena D. Milosevic, Kralovics, Robert, Orkin, Stuart H., Skoda, Radek C.
Wydane w J Exp Med (2016)

JAK2-V617F and interferon-α induce megakaryocyte-biased stem cells characterized by decreased long-term functionality

od Rao, Tata Nageswara, Hansen, Nils, Stetka, Jan, Luque Paz, Damien, Kalmer, Milena, Hilfiker, Julian, Endele, Max, Ahmed, Nouraiz, Kubovcakova, Lucia, Rybarikova, Margareta, Hao-Shen, Hui, Geier, Florian, Beisel, Christian, Dirnhofer, Stefan, Schroeder, Timm, Brümmendorf, Tim H., Wolf, Dominik, Koschmieder, Steffen, Skoda, Radek C.
Wydane w Blood (2021)

Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms

od Stivala, Simona, Codilupi, Tamara, Brkic, Sime, Baerenwaldt, Anne, Ghosh, Nilabh, Hao-Shen, Hui, Dirnhofer, Stephan, Dettmer, Matthias S., Simillion, Cedric, Kaufmann, Beat A., Chiu, Sophia, Keller, Matthew, Kleppe, Maria, Hilpert, Morgane, Buser, Andreas S., Passweg, Jakob R., Radimerski, Thomas, Skoda, Radek C., Levine, Ross L., Meyer, Sara C.
Wydane w J Clin Invest (2019)

JAK2-mutant hematopoietic cells display metabolic alterations that can be targeted to treat myeloproliferative neoplasms

od Rao, Tata Nageswara, Hansen, Nils, Hilfiker, Julian, Rai, Shivam, Majewska, Julia-Magdalena, Leković, Danijela, Gezer, Deniz, Andina, Nicola, Galli, Serena, Cassel, Teresa, Geier, Florian, Delezie, Julien, Nienhold, Ronny, Hao-Shen, Hui, Beisel, Christian, Di Palma, Serena, Dimeloe, Sarah, Trebicka, Jonel, Wolf, Dominik, Gassmann, Max, Fan, Teresa W.-M., Lane, Andrew N., Handschin, Christoph, Dirnhofer, Stefan, Kröger, Nicolaus, Hess, Christoph, Radimerski, Thomas, Koschmieder, Steffen, Čokić, Vladan P., Skoda, Radek C.
Wydane w Blood (2019)