Selective deletion of Jak2 in adult mouse hematopoietic cells leads to lethal anemia and thrombocytopenia

nork Grisouard, Jean, Hao-Shen, Hui, Dirnhofer, Stephan, Wagner, Kay-Uwe, Skoda, Radek C.
Argitaratua 2014

Myeloproliferative neoplasms can be initiated from a single hematopoietic stem cell expressing JAK2-V617F

nork Lundberg, Pontus, Takizawa, Hitoshi, Kubovcakova, Lucia, Guo, Guoji, Hao-Shen, Hui, Dirnhofer, Stephan, Orkin, Stuart H., Manz, Markus G., Skoda, Radek C.
Argitaratua 2014

Loss of Ezh2 synergizes with JAK2-V617F in initiating myeloproliferative neoplasms and promoting myelofibrosis

nork Shimizu, Takafumi, Kubovcakova, Lucia, Nienhold, Ronny, Zmajkovic, Jakub, Meyer, Sara C., Hao-Shen, Hui, Geier, Florian, Dirnhofer, Stephan, Guglielmelli, Paola, Vannucchi, Alessandro M., Feenstra, Jelena D. Milosevic, Kralovics, Robert, Orkin, Stuart H., Skoda, Radek C.
Argitaratua izan da J Exp Med (2016)

JAK2-V617F and interferon-α induce megakaryocyte-biased stem cells characterized by decreased long-term functionality

nork Rao, Tata Nageswara, Hansen, Nils, Stetka, Jan, Luque Paz, Damien, Kalmer, Milena, Hilfiker, Julian, Endele, Max, Ahmed, Nouraiz, Kubovcakova, Lucia, Rybarikova, Margareta, Hao-Shen, Hui, Geier, Florian, Beisel, Christian, Dirnhofer, Stefan, Schroeder, Timm, Brümmendorf, Tim H., Wolf, Dominik, Koschmieder, Steffen, Skoda, Radek C.
Argitaratua izan da Blood (2021)

Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms

nork Stivala, Simona, Codilupi, Tamara, Brkic, Sime, Baerenwaldt, Anne, Ghosh, Nilabh, Hao-Shen, Hui, Dirnhofer, Stephan, Dettmer, Matthias S., Simillion, Cedric, Kaufmann, Beat A., Chiu, Sophia, Keller, Matthew, Kleppe, Maria, Hilpert, Morgane, Buser, Andreas S., Passweg, Jakob R., Radimerski, Thomas, Skoda, Radek C., Levine, Ross L., Meyer, Sara C.
Argitaratua izan da J Clin Invest (2019)

JAK2-mutant hematopoietic cells display metabolic alterations that can be targeted to treat myeloproliferative neoplasms

nork Rao, Tata Nageswara, Hansen, Nils, Hilfiker, Julian, Rai, Shivam, Majewska, Julia-Magdalena, Leković, Danijela, Gezer, Deniz, Andina, Nicola, Galli, Serena, Cassel, Teresa, Geier, Florian, Delezie, Julien, Nienhold, Ronny, Hao-Shen, Hui, Beisel, Christian, Di Palma, Serena, Dimeloe, Sarah, Trebicka, Jonel, Wolf, Dominik, Gassmann, Max, Fan, Teresa W.-M., Lane, Andrew N., Handschin, Christoph, Dirnhofer, Stefan, Kröger, Nicolaus, Hess, Christoph, Radimerski, Thomas, Koschmieder, Steffen, Čokić, Vladan P., Skoda, Radek C.
Argitaratua izan da Blood (2019)