Mitotic Checkpoint Kinase Mps1 Has a Role in Normal Physiology which Impacts Clinical Utility

gan Martinez, Ricardo, Blasina, Alessandra, Hallin, Jill F., Hu, Wenyue, Rymer, Isha, Fan, Jeffery, Hoffman, Robert L., Murphy, Sean, Marx, Matthew, Yanochko, Gina, Trajkovic, Dusko, Dinh, Dac, Timofeevski, Sergei, Zhu, Zhou, Sun, Peiquing, Lappin, Patrick B., Murray, Brion W.
Cyhoeddwyd yn PLoS One (2015)

Discovery of Tetrahydropyridopyrimidines as Irreversible Covalent Inhibitors of KRAS-G12C with In Vivo Activity

gan Fell, Jay B., Fischer, John P., Baer, Brian R., Ballard, Joshua, Blake, James F., Bouhana, Karyn, Brandhuber, Barbara J., Briere, David M., Burgess, Laurence E., Burkard, Michael R., Chiang, Harrah, Chicarelli, Mark J., Davidson, Kevin, Gaudino, John J., Hallin, Jill, Hanson, Lauren, Hee, Kenneth, Hicken, Erik J., Hinklin, Ronald J., Marx, Matthew A., Mejia, Macedonio J., Olson, Peter, Savechenkov, Pavel, Sudhakar, Niranjan, Tang, Tony P., Vigers, Guy P., Zecca, Henry, Christensen, James G.
Cyhoeddwyd yn ACS Med Chem Lett (2018)

The KRAS(G12C) Inhibitor, MRTX849, Provides Insight Toward Therapeutic Susceptibility of KRAS Mutant Cancers in Mouse Models and Patients

gan Hallin, Jill, Engstrom, Lars D., Hargis, Lauren, Calinisan, Andrew, Aranda, Ruth, Briere, David M., Sudhakar, Niranjan, Bowcut, Vickie, Baer, Brian R., Ballard, Joshua A., Burkard, Michael R., Fell, Jay B., Fischer, John P., Vigers, Guy P., Xue, Yaohua, Gatto, Sole, Fernandez-Banet, Julio, Pavlicek, Adam, Velastagui, Karen, Chao, Richard C., Barton, Jeremy, Pierobon, Mariaelena, Baldelli, Elisa, Petricoin, Emanuel F., Cassidy, Douglas P., Marx, Matthew A., Rybkin, Igor I., Johnson, Melissa L., Ou, Sai-Hong Ignatius, Lito, Piro, Papadopoulos, Kyriakos P., Jänne, Pasi A., Olson, Peter, Christensen, James G.
Cyhoeddwyd yn Cancer Discov (2019)