Sir2 mediates longevity in the fly through a pathway related to calorie restriction

Por Rogina, Blanka, Helfand, Stephen L.
Publicado em 2004

Indy Mutations and Drosophila Longevity

Por Rogina, Blanka, Helfand, Stephen L.
Publicado em 2013

New tricks of an old molecule: lifespan regulation by p53

Por Bauer, Johannes H, Helfand, Stephen L
Publicado em 2006

Sir2 and longevity: The p53 connection

Por Bauer, Johannes H., Helfand, Stephen L.
Publicado em 2009

Indy knockdown in mice mimics elements of dietary restriction

Por Shulman, Gerald I., Helfand, Stephen L.
Publicado em 2011

Chromatin structure and transposable elements in organismal aging

Por Wood, Jason G., Helfand, Stephen L.
Publicado em 2013

Drosophila drop-dead mutations accelerate the time course of age-related markers

Por Rogina, Blanka, Benzer, Seymour, Helfand, Stephen L.
Publicado em 1997

The longevity transporter mIndy (Slc13a5) as a target for treating hepatic steatosis and insulin resistance

Por Willmes, Diana M., Helfand, Stephen L., Birkenfeld, Andreas L.
Publicado no Aging (Albany NY) (2016)

Involvement of Drosophila Uncoupling Protein 5 in Metabolism and Aging

Por Sánchez-Blanco, Adolfo, Fridell, Yih-Woei C., Helfand, Stephen L.
Publicado em 2006

Reply to Partridge et al.: Longevity of Drosophila Indy mutant is influenced by caloric intake and genetic background

Por Helfand, Stephen L., Neretti, Nicola, Wang, Pei-Yu, Rogina, Blanka
Publicado em 2009

Functional characterization and immunolocalization of the transporter encoded by the life-extending gene Indy

Por Knauf, Felix, Rogina, Blanka, Jiang, Zhirong, Aronson, Peter S., Helfand, Stephen L.
Publicado em 2002

Conditional tradeoffs between aging and organismal performance of Indy long-lived mutant flies

Por Marden, James H., Rogina, Blanka, Montooth, Kristi L., Helfand, Stephen L.
Publicado em 2003

An accelerated assay for the identification of lifespan-extending interventions in Drosophila melanogaster

Por Bauer, Johannes H., Goupil, Stephan, Garber, Graham B., Helfand, Stephen L.
Publicado em 2004

Indy gene variation in natural populations confers fitness advantage and life span extension through transposon insertion

Por Zhu, Chen-Tseh, Chang, Chengyi, Reenan, Robert A., Helfand, Stephen L.
Publicado em 2014

Sleeping dogs of the genome: Retrotransposable elements may be agents of somatic diversity, disease and aging

Por Gorbunova, Vera, Boeke, Jef D., Helfand, Stephen L., Sedivy, John M.
Publicado no Science (2014)

New comparative genomics approach reveals a conserved health span signature across species

Por Antosh, Michael, Fox, David, Helfand, Stephen L., Cooper, Leon N, Neretti, Nicola
Publicado em 2011

Dominant-negative Dmp53 extends life span through the dTOR pathway in D. melanogaster

Por Bauer, Johannes H., Chang, Chengyi, Bae, Gina, Morris, Siti Nur Sarah, Helfand, Stephen L.
Publicado em 2010

Dietary switch reveals fast coordinated gene expression changes in Drosophila melanogaster

Por Whitaker, Rachel, Gil, M. Pilar, Ding, Feifei, Tatar, Marc, Helfand, Stephen L., Neretti, Nicola
Publicado em 2014

Comparative transcriptional profiling identifies takeout as a gene that regulates life span

Por Bauer, Johannes, Antosh, Michael, Chang, Chengyi, Schorl, Christoph, Kolli, Santharam, Neretti, Nicola, Helfand, Stephen L.
Publicado em 2010

Increased expression of Drosophila Sir 2 extends life span in a dose-dependent manner

Por Whitaker, Rachel, Faulkner, Shakeela, Miyokawa, Reika, Burhenn, Lucas, Henriksen, Mark, Wood, Jason G., Helfand, Stephen L.
Publicado em 2013