Optimisation of substrate feeding in shake flask cultures of <it>Pichia pastoris </it>for recombinant protein production

per Myllyharju Johanna, Neubauer Antje, Hämäläinen Eija-Riitta, Vasala Antti, Krause Mirja, Ruottinen Maria, Bollok Monika, Neubauer Peter
Publicat 2006-10-01

Improved production of human type II procollagen in the yeast Pichia pastoris in shake flasks by a wireless-controlled fed-batch system

per Ruottinen, Maria, Bollok, Monika, Kögler, Martin, Neubauer, Antje, Krause, Mirja, Hämäläinen, Eija-Riitta, Myllyharju, Johanna, Vasala, Antti, Neubauer, Peter
Publicat 2008

The Collagen V Homotrimer [α1(V)](3) Production Is Unexpectedly Favored over the Heterotrimer [α1(V)](2)α2(V) in Recombinant Expression Systems

per Roulet, Muriel, Välkkilä, Merja, Chanut-Delalande, Hélène, Hämäläinen, Eija-Riitta, Kessler, Efrat, Ala-Kokko, Leena, Männikkö, Minna, Bonod-Bidaud, Christelle, Ruggiero, Florence
Publicat 2010

The first trimester human placenta is a site for terminal maturation of primitive erythroid cells

per Van Handel, Ben, Prashad, Sacha L., Hassanzadeh-Kiabi, Nargess, Huang, Andy, Magnusson, Mattias, Atanassova, Boriana, Chen, Angela, Hamalainen, Eija I., Mikkola, Hanna K. A.
Publicat 2010

An Immune Response Network Associated with Blood Lipid Levels

per Inouye, Michael, Silander, Kaisa, Hamalainen, Eija, Salomaa, Veikko, Harald, Kennet, Jousilahti, Pekka, Männistö, Satu, Eriksson, Johan G., Saarela, Janna, Ripatti, Samuli, Perola, Markus, van Ommen, Gert-Jan B., Taskinen, Marja-Riitta, Palotie, Aarno, Dermitzakis, Emmanouil T., Peltonen, Leena
Publicat 2010

Metabonomic, transcriptomic, and genomic variation of a population cohort

per Inouye, Michael, Kettunen, Johannes, Soininen, Pasi, Silander, Kaisa, Ripatti, Samuli, Kumpula, Linda S, Hämäläinen, Eija, Jousilahti, Pekka, Kangas, Antti J, Männistö, Satu, Savolainen, Markku J, Jula, Antti, Leiviskä, Jaana, Palotie, Aarno, Salomaa, Veikko, Perola, Markus, Ala-Korpela, Mika, Peltonen, Leena
Publicat 2010

Chromosome 19p13 Loci in Finnish Migraine With Aura Families

per Kaunisto, Mari A., Tikka, Päivi J., Kallela, Mikko, Leal, Suzanne M., Papp, Jeanette C., Korhonen, Arja, Hämäläinen, Eija, Harno, Hanna, Havanka, Hannele, Nissilä, Markku, Säkö, Erkki, Ilmavirta, Matti, Kaprio, Jaakko, Färkkilä, Markus, Ophoff, Roel A., Palotie, Aarno, Wessman, Maija
Publicat a Am J Med Genet B Neuropsychiatr Genet (2005)

Consistently Replicating Locus Linked to Migraine on 10q22-q23

per Anttila, Verneri, Nyholt, Dale R., Kallela, Mikko, Artto, Ville, Vepsäläinen, Salli, Jakkula, Eveliina, Wennerström, Annika, Tikka-Kleemola, Päivi, Kaunisto, Mari A., Hämäläinen, Eija, Widén, Elisabeth, Terwilliger, Joseph, Merikangas, Kathleen, Montgomery, Grant W., Martin, Nicholas G., Daly, Mark, Kaprio, Jaakko, Peltonen, Leena, Färkkilä, Markus, Wessman, Maija, Palotie, Aarno
Publicat 2008

A Susceptibility Locus for Migraine with Aura, on Chromosome 4q24

per Wessman, Maija, Kallela, Mikko, Kaunisto, Mari A., Marttila, Pia, Sobel, Eric, Hartiala, Jaana, Oswell, Greg, Leal, Suzanne M., Papp, Jeanette C., Hämäläinen, Eija, Broas, Petra, Joslyn, Geoffrey, Hovatta, Iiris, Hiekkalinna, Tero, Kaprio, Jaakko, Ott, Jürg, Cantor, Rita M., Zwart, John-Anker, Ilmavirta, Matti, Havanka, Hannele, Färkkilä, Markus, Peltonen, Leena, Palotie, Aarno
Publicat 2002

Use of Cancer-Specific Genomic Rearrangements to Quantify Disease Burden in Plasma from Patients with Solid Tumors

per McBride, David J., Orpana, Arto K., Sotiriou, Christos, Joensuu, Heikki, Stephens, Philip J., Mudie, Laura J., Hämälaïnen, Eija, Stebbings, Lucy A., Andersson, Leif C., Flanagan, Adrienne M., Durbecq, Virginie, Ignatiadis, Michail, Kallioniemi, Olli, Heckman, Caroline A., Alitalo, Kari, Edgren, Henrik, Futreal, P. Andrew, Stratton, Michael R., Campbell, Peter J.
Publicat 2010

Contribution of rare and common variants to intellectual disability in a sub-isolate of Northern Finland

per Kurki, Mitja I., Saarentaus, Elmo, Pietiläinen, Olli, Gormley, Padhraig, Lal, Dennis, Kerminen, Sini, Torniainen-Holm, Minna, Hämäläinen, Eija, Rahikkala, Elisa, Keski-Filppula, Riikka, Rauhala, Merja, Korpi-Heikkilä, Satu, Komulainen–Ebrahim, Jonna, Helander, Heli, Vieira, Päivi, Männikkö, Minna, Peltonen, Markku, Havulinna, Aki S., Salomaa, Veikko, Pirinen, Matti, Suvisaari, Jaana, Moilanen, Jukka S., Körkkö, Jarmo, Kuismin, Outi, Daly, Mark J., Palotie, Aarno
Publicat a Nat Commun (2019)

Genome-wide Polygenic Burden of Rare Deleterious Variants in Sudden Unexpected Death in Epilepsy

per Leu, Costin, Balestrini, Simona, Maher, Bridget, Hernández-Hernández, Laura, Gormley, Padhraig, Hämäläinen, Eija, Heggeli, Kristin, Schoeler, Natasha, Novy, Jan, Willis, Joseph, Plagnol, Vincent, Ellis, Rachael, Reavey, Eleanor, O'Regan, Mary, Pickrell, William O., Thomas, Rhys H., Chung, Seo-Kyung, Delanty, Norman, McMahon, Jacinta M., Malone, Stephen, Sadleir, Lynette G., Berkovic, Samuel F., Nashef, Lina, Zuberi, Sameer M., Rees, Mark I., Cavalleri, Gianpiero L., Sander, Josemir W., Hughes, Elaine, Helen Cross, J., Scheffer, Ingrid E., Palotie, Aarno, Sisodiya, Sanjay M.
Publicat a EBioMedicine (2015)

Common variant burden contributes to the familial aggregation of migraine in 1,589 families

per Gormley, Padhraig, Kurki, Mitja I., Hiekkala, Marjo Eveliina, Veerapen, Kumar, Häppölä, Paavo, Mitchell, Adele A., Lal, Dennis, Palta, Priit, Surakka, Ida, Kaunisto, Mari Anneli, Hämäläinen, Eija, Vepsäläinen, Salli, Havanka, Hannele, Harno, Hanna, Ilmavirta, Matti, Nissilä, Markku, Säkö, Erkki, Sumelahti, Marja-Liisa, Liukkonen, Jarmo, Sillanpää, Matti, Metsähonkala, Liisa, Koskinen, Seppo, Lehtimäki, Terho, Raitakari, Olli, Männikkö, Minna, Ran, Caroline, Belin, Andrea Carmine, Jousilahti, Pekka, Anttila, Verneri, Salomaa, Veikko, Artto, Ville, Färkkilä, Markus, Runz, Heiko, Daly, Mark J., Neale, Benjamin M., Ripatti, Samuli, Kallela, Mikko, Wessman, Maija, Palotie, Aarno
Publicat a Neuron (2018)

A high-density association screen of 155 ion transport genes for involvement with common migraine

per Nyholt, Dale R., LaForge, K. Steven, Kallela, Mikko, Alakurtti, Kirsi, Anttila, Verneri, Färkkilä, Markus, Hämaläinen, Eija, Kaprio, Jaakko, Kaunisto, Mari A., Heath, Andrew C., Montgomery, Grant W., Göbel, Hartmut, Todt, Unda, Ferrari, Michel D., Launer, Lenore J., Frants, Rune R., Terwindt, Gisela M., de Vries, Boukje, Verschuren, W.M. Monique, Brand, Jan, Freilinger, Tobias, Pfaffenrath, Volker, Straube, Andreas, Ballinger, Dennis G., Zhan, Yiping, Daly, Mark J., Cox, David R., Dichgans, Martin, van den Maagdenberg, Arn M.J.M., Kubisch, Christian, Martin, Nicholas G., Wessman, Maija, Peltonen, Leena, Palotie, Aarno
Publicat 2008

Migraine without aura: genome-wide association analysis identifies several novel susceptibility

per de Vries, Boukje, Freilinger, Tobias, Anttila, Verneri, Malik, Rainer, Kallela, Mikko, Terwindt, Gisela M, Pozo-Rosich, Patricia, Winsvold, Bendik, Nyholt, Dale R, van Oosterhout, Willebrordus PJ, Artto, Ville, Todt, Unda, Hämäläinen, Eija, Fernández-Morales, Jèssica, Louter, Mark A, Kaunisto, Mari A, Schoenen, Jean, Raitakari, Olli, Lehtimäki, Terho, Vila-Pueyo, Marta, Göbel, Hartmut, Wichmann, Erich, Sintas, Cèlia, Uitterlinden, Andre G, Hofman, Albert, Rivadeneira, Fernando, Heinze, Axel, Tronvik, Erling, van Duijn, Cornelia M, Kaprio, Jaakko, Cormand, Bru, Wessman, Maija, Frants, Rune R, Meitinger, Thomas, Müller-Myhsok, Bertram, Zwart, John-Anker, Färkkilä, Markus, Macaya, Alfons, Ferrari, Michel D, Kubisch, Christian, Palotie, Aarno, Dichgans, Martin, van den Maagdenberg, Arn MJM
Publicat 2013

Genome-wide association analysis identifies susceptibility loci for migraine without aura

per Freilinger, Tobias, Anttila, Verneri, de Vries, Boukje, Malik, Rainer, Kallela, Mikko, Terwindt, Gisela M, Pozo-Rosich, Patricia, Winsvold, Bendik, Nyholt, Dale R, van Oosterhout, Willebrordus P J, Artto, Ville, Todt, Unda, Hämäläinen, Eija, Fernández-Morales, Jèssica, Louter, Mark A, Kaunisto, Mari A, Schoenen, Jean, Raitakari, Olli, Lehtimäki, Terho, Vila-Pueyo, Marta, Göbel, Hartmut, Wichmann, Erich, Sintas, Cèlia, Uitterlinden, Andre G, Hofman, Albert, Rivadeneira, Fernando, Heinze, Axel, Tronvik, Erling, van Duijn, Cornelia M., Kaprio, Jaakko, Cormand, Bru, Wessman, Maija, Frants, Rune R, Meitinger, Thomas, Müller-Myhsok, Bertram, Zwart, John-Anker, Färkkilä, Markus, Macaya, Alfons, Ferrari, Michel D, Kubisch, Christian, Palotie, Aarno, Dichgans, Martin, van den Maagdenberg, Arn M J M
Publicat 2012

Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum

per Ganna, Andrea, Satterstrom, F. Kyle, Zekavat, Seyedeh M., Das, Indraniel, Kurki, Mitja I., Churchhouse, Claire, Alfoldi, Jessica, Martin, Alicia R., Havulinna, Aki S., Byrnes, Andrea, Thompson, Wesley K., Nielsen, Philip R., Karczewski, Konrad J., Saarentaus, Elmo, Rivas, Manuel A., Gupta, Namrata, Pietiläinen, Olli, Emdin, Connor A., Lescai, Francesco, Bybjerg-Grauholm, Jonas, Flannick, Jason, Mercader, Josep M., Udler, Miriam, Laakso, Markku, Salomaa, Veikko, Hultman, Christina, Ripatti, Samuli, Hämäläinen, Eija, Moilanen, Jukka S., Körkkö, Jarmo, Kuismin, Outi, Nordentoft, Merete, Hougaard, David M., Mors, Ole, Werge, Thomas, Mortensen, Preben Bo, MacArthur, Daniel, Daly, Mark J., Sullivan, Patrick F., Locke, Adam E., Palotie, Aarno, Børglum, Anders D., Kathiresan, Sekar, Neale, Benjamin M.
Publicat a Am J Hum Genet (2018)

Pitfalls in genetic testing: the story of missed SCN1A mutations

per Djémié, Tania, Weckhuysen, Sarah, von Spiczak, Sarah, Carvill, Gemma L., Jaehn, Johanna, Anttonen, Anna‐Kaisa, Brilstra, Eva, Caglayan, Hande S., de Kovel, Carolien G., Depienne, Christel, Gaily, Eija, Gennaro, Elena, Giraldez, Beatriz G., Gormley, Padhraig, Guerrero‐López, Rosa, Guerrini, Renzo, Hämäläinen, Eija, Hartmann, Corinna, Hernandez‐Hernandez, Laura, Hjalgrim, Helle, Koeleman, Bobby P. C., Leguern, Eric, Lehesjoki, Anna‐Elina, Lemke, Johannes R., Leu, Costin, Marini, Carla, McMahon, Jacinta M., Mei, Davide, Møller, Rikke S., Muhle, Hiltrud, Myers, Candace T., Nava, Caroline, Serratosa, Jose M., Sisodiya, Sanjay M., Stephani, Ulrich, Striano, Pasquale, van Kempen, Marjan J. A., Verbeek, Nienke E., Usluer, Sunay, Zara, Federico, Palotie, Aarno, Mefford, Heather C., Scheffer, Ingrid E., De Jonghe, Peter, Helbig, Ingo, Suls, Arvid
Publicat a Mol Genet Genomic Med (2016)

Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population

per Lim, Elaine T., Würtz, Peter, Havulinna, Aki S., Palta, Priit, Tukiainen, Taru, Rehnström, Karola, Esko, Tõnu, Mägi, Reedik, Inouye, Michael, Lappalainen, Tuuli, Chan, Yingleong, Salem, Rany M., Lek, Monkol, Flannick, Jason, Sim, Xueling, Manning, Alisa, Ladenvall, Claes, Bumpstead, Suzannah, Hämäläinen, Eija, Aalto, Kristiina, Maksimow, Mikael, Salmi, Marko, Blankenberg, Stefan, Ardissino, Diego, Shah, Svati, Horne, Benjamin, McPherson, Ruth, Hovingh, Gerald K., Reilly, Muredach P., Watkins, Hugh, Goel, Anuj, Farrall, Martin, Girelli, Domenico, Reiner, Alex P., Stitziel, Nathan O., Kathiresan, Sekar, Gabriel, Stacey, Barrett, Jeffrey C., Lehtimäki, Terho, Laakso, Markku, Groop, Leif, Kaprio, Jaakko, Perola, Markus, McCarthy, Mark I., Boehnke, Michael, Altshuler, David M., Lindgren, Cecilia M., Hirschhorn, Joel N., Metspalu, Andres, Freimer, Nelson B., Zeller, Tanja, Jalkanen, Sirpa, Koskinen, Seppo, Raitakari, Olli, Durbin, Richard, MacArthur, Daniel G., Salomaa, Veikko, Ripatti, Samuli, Daly, Mark J., Palotie, Aarno
Publicat 2014

Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1

per Anttila, Verneri, Stefansson, Hreinn, Kallela, Mikko, Todt, Unda, Terwindt, Gisela M, Calafato, M Stella, Nyholt, Dale R, Dimas, Antigone S, Freilinger, Tobias, Müller-Myhsok, Bertram, Artto, Ville, Inouye, Michael, Alakurtti, Kirsi, Kaunisto, Mari A, Hämäläinen, Eija, de Vries, Boukje, Stam, Anine H, Weller, Claudia M, Heinze, Axel, Heinze-Kuhn, Katja, Goebel, Ingrid, Borck, Guntram, Göbel, Hartmut, Steinberg, Stacy, Wolf, Christiane, Björnsson, Asgeir, Gudmundsson, Gretar, Kirchmann, Malene, Hauge, Anne, Werge, Thomas, Schoenen, Jean, Eriksson, Johan G, Hagen, Knut, Stovner, Lars, Wichmann, H-Erich, Meitinger, Thomas, Alexander, Michael, Moebus, Susanne, Schreiber, Stefan, Aulchenko, Yurii S, Breteler, Monique M B, Uitterlinden, Andre G, Hofman, Albert, van Duijn, Cornelia M, Tikka-Kleemola, Päivi, Vepsäläinen, Salli, Lucae, Susanne, Tozzi, Federica, Muglia, Pierandrea, Barrett, Jeffrey, Kaprio, Jaakko, Färkkilä, Markus, Peltonen, Leena, Stefansson, Kari, Zwart, John-Anker, Ferrari, Michel D, Olesen, Jes, Daly, Mark, Wessman, Maija, van den Maagdenberg, Arn M J M, Dichgans, Martin, Kubisch, Christian, Dermitzakis, Emmanouil T, Frants, Rune R, Palotie, Aarno
Publicat 2010