Optimisation of substrate feeding in shake flask cultures of <it>Pichia pastoris </it>for recombinant protein production

Por Myllyharju Johanna, Neubauer Antje, Hämäläinen Eija-Riitta, Vasala Antti, Krause Mirja, Ruottinen Maria, Bollok Monika, Neubauer Peter
Publicado em 2006-10-01

Improved production of human type II procollagen in the yeast Pichia pastoris in shake flasks by a wireless-controlled fed-batch system

Por Ruottinen, Maria, Bollok, Monika, Kögler, Martin, Neubauer, Antje, Krause, Mirja, Hämäläinen, Eija-Riitta, Myllyharju, Johanna, Vasala, Antti, Neubauer, Peter
Publicado em 2008

The Collagen V Homotrimer [α1(V)](3) Production Is Unexpectedly Favored over the Heterotrimer [α1(V)](2)α2(V) in Recombinant Expression Systems

Por Roulet, Muriel, Välkkilä, Merja, Chanut-Delalande, Hélène, Hämäläinen, Eija-Riitta, Kessler, Efrat, Ala-Kokko, Leena, Männikkö, Minna, Bonod-Bidaud, Christelle, Ruggiero, Florence
Publicado em 2010

The first trimester human placenta is a site for terminal maturation of primitive erythroid cells

Por Van Handel, Ben, Prashad, Sacha L., Hassanzadeh-Kiabi, Nargess, Huang, Andy, Magnusson, Mattias, Atanassova, Boriana, Chen, Angela, Hamalainen, Eija I., Mikkola, Hanna K. A.
Publicado em 2010

An Immune Response Network Associated with Blood Lipid Levels

Por Inouye, Michael, Silander, Kaisa, Hamalainen, Eija, Salomaa, Veikko, Harald, Kennet, Jousilahti, Pekka, Männistö, Satu, Eriksson, Johan G., Saarela, Janna, Ripatti, Samuli, Perola, Markus, van Ommen, Gert-Jan B., Taskinen, Marja-Riitta, Palotie, Aarno, Dermitzakis, Emmanouil T., Peltonen, Leena
Publicado em 2010

Metabonomic, transcriptomic, and genomic variation of a population cohort

Por Inouye, Michael, Kettunen, Johannes, Soininen, Pasi, Silander, Kaisa, Ripatti, Samuli, Kumpula, Linda S, Hämäläinen, Eija, Jousilahti, Pekka, Kangas, Antti J, Männistö, Satu, Savolainen, Markku J, Jula, Antti, Leiviskä, Jaana, Palotie, Aarno, Salomaa, Veikko, Perola, Markus, Ala-Korpela, Mika, Peltonen, Leena
Publicado em 2010

Chromosome 19p13 Loci in Finnish Migraine With Aura Families

Por Kaunisto, Mari A., Tikka, Päivi J., Kallela, Mikko, Leal, Suzanne M., Papp, Jeanette C., Korhonen, Arja, Hämäläinen, Eija, Harno, Hanna, Havanka, Hannele, Nissilä, Markku, Säkö, Erkki, Ilmavirta, Matti, Kaprio, Jaakko, Färkkilä, Markus, Ophoff, Roel A., Palotie, Aarno, Wessman, Maija
Publicado no Am J Med Genet B Neuropsychiatr Genet (2005)

Consistently Replicating Locus Linked to Migraine on 10q22-q23

Por Anttila, Verneri, Nyholt, Dale R., Kallela, Mikko, Artto, Ville, Vepsäläinen, Salli, Jakkula, Eveliina, Wennerström, Annika, Tikka-Kleemola, Päivi, Kaunisto, Mari A., Hämäläinen, Eija, Widén, Elisabeth, Terwilliger, Joseph, Merikangas, Kathleen, Montgomery, Grant W., Martin, Nicholas G., Daly, Mark, Kaprio, Jaakko, Peltonen, Leena, Färkkilä, Markus, Wessman, Maija, Palotie, Aarno
Publicado em 2008

A Susceptibility Locus for Migraine with Aura, on Chromosome 4q24

Por Wessman, Maija, Kallela, Mikko, Kaunisto, Mari A., Marttila, Pia, Sobel, Eric, Hartiala, Jaana, Oswell, Greg, Leal, Suzanne M., Papp, Jeanette C., Hämäläinen, Eija, Broas, Petra, Joslyn, Geoffrey, Hovatta, Iiris, Hiekkalinna, Tero, Kaprio, Jaakko, Ott, Jürg, Cantor, Rita M., Zwart, John-Anker, Ilmavirta, Matti, Havanka, Hannele, Färkkilä, Markus, Peltonen, Leena, Palotie, Aarno
Publicado em 2002

Use of Cancer-Specific Genomic Rearrangements to Quantify Disease Burden in Plasma from Patients with Solid Tumors

Por McBride, David J., Orpana, Arto K., Sotiriou, Christos, Joensuu, Heikki, Stephens, Philip J., Mudie, Laura J., Hämälaïnen, Eija, Stebbings, Lucy A., Andersson, Leif C., Flanagan, Adrienne M., Durbecq, Virginie, Ignatiadis, Michail, Kallioniemi, Olli, Heckman, Caroline A., Alitalo, Kari, Edgren, Henrik, Futreal, P. Andrew, Stratton, Michael R., Campbell, Peter J.
Publicado em 2010

Contribution of rare and common variants to intellectual disability in a sub-isolate of Northern Finland

Por Kurki, Mitja I., Saarentaus, Elmo, Pietiläinen, Olli, Gormley, Padhraig, Lal, Dennis, Kerminen, Sini, Torniainen-Holm, Minna, Hämäläinen, Eija, Rahikkala, Elisa, Keski-Filppula, Riikka, Rauhala, Merja, Korpi-Heikkilä, Satu, Komulainen–Ebrahim, Jonna, Helander, Heli, Vieira, Päivi, Männikkö, Minna, Peltonen, Markku, Havulinna, Aki S., Salomaa, Veikko, Pirinen, Matti, Suvisaari, Jaana, Moilanen, Jukka S., Körkkö, Jarmo, Kuismin, Outi, Daly, Mark J., Palotie, Aarno
Publicado no Nat Commun (2019)

Genome-wide Polygenic Burden of Rare Deleterious Variants in Sudden Unexpected Death in Epilepsy

Por Leu, Costin, Balestrini, Simona, Maher, Bridget, Hernández-Hernández, Laura, Gormley, Padhraig, Hämäläinen, Eija, Heggeli, Kristin, Schoeler, Natasha, Novy, Jan, Willis, Joseph, Plagnol, Vincent, Ellis, Rachael, Reavey, Eleanor, O'Regan, Mary, Pickrell, William O., Thomas, Rhys H., Chung, Seo-Kyung, Delanty, Norman, McMahon, Jacinta M., Malone, Stephen, Sadleir, Lynette G., Berkovic, Samuel F., Nashef, Lina, Zuberi, Sameer M., Rees, Mark I., Cavalleri, Gianpiero L., Sander, Josemir W., Hughes, Elaine, Helen Cross, J., Scheffer, Ingrid E., Palotie, Aarno, Sisodiya, Sanjay M.
Publicado no EBioMedicine (2015)

Common variant burden contributes to the familial aggregation of migraine in 1,589 families

Por Gormley, Padhraig, Kurki, Mitja I., Hiekkala, Marjo Eveliina, Veerapen, Kumar, Häppölä, Paavo, Mitchell, Adele A., Lal, Dennis, Palta, Priit, Surakka, Ida, Kaunisto, Mari Anneli, Hämäläinen, Eija, Vepsäläinen, Salli, Havanka, Hannele, Harno, Hanna, Ilmavirta, Matti, Nissilä, Markku, Säkö, Erkki, Sumelahti, Marja-Liisa, Liukkonen, Jarmo, Sillanpää, Matti, Metsähonkala, Liisa, Koskinen, Seppo, Lehtimäki, Terho, Raitakari, Olli, Männikkö, Minna, Ran, Caroline, Belin, Andrea Carmine, Jousilahti, Pekka, Anttila, Verneri, Salomaa, Veikko, Artto, Ville, Färkkilä, Markus, Runz, Heiko, Daly, Mark J., Neale, Benjamin M., Ripatti, Samuli, Kallela, Mikko, Wessman, Maija, Palotie, Aarno
Publicado no Neuron (2018)

A high-density association screen of 155 ion transport genes for involvement with common migraine

Por Nyholt, Dale R., LaForge, K. Steven, Kallela, Mikko, Alakurtti, Kirsi, Anttila, Verneri, Färkkilä, Markus, Hämaläinen, Eija, Kaprio, Jaakko, Kaunisto, Mari A., Heath, Andrew C., Montgomery, Grant W., Göbel, Hartmut, Todt, Unda, Ferrari, Michel D., Launer, Lenore J., Frants, Rune R., Terwindt, Gisela M., de Vries, Boukje, Verschuren, W.M. Monique, Brand, Jan, Freilinger, Tobias, Pfaffenrath, Volker, Straube, Andreas, Ballinger, Dennis G., Zhan, Yiping, Daly, Mark J., Cox, David R., Dichgans, Martin, van den Maagdenberg, Arn M.J.M., Kubisch, Christian, Martin, Nicholas G., Wessman, Maija, Peltonen, Leena, Palotie, Aarno
Publicado em 2008

Migraine without aura: genome-wide association analysis identifies several novel susceptibility

Por de Vries, Boukje, Freilinger, Tobias, Anttila, Verneri, Malik, Rainer, Kallela, Mikko, Terwindt, Gisela M, Pozo-Rosich, Patricia, Winsvold, Bendik, Nyholt, Dale R, van Oosterhout, Willebrordus PJ, Artto, Ville, Todt, Unda, Hämäläinen, Eija, Fernández-Morales, Jèssica, Louter, Mark A, Kaunisto, Mari A, Schoenen, Jean, Raitakari, Olli, Lehtimäki, Terho, Vila-Pueyo, Marta, Göbel, Hartmut, Wichmann, Erich, Sintas, Cèlia, Uitterlinden, Andre G, Hofman, Albert, Rivadeneira, Fernando, Heinze, Axel, Tronvik, Erling, van Duijn, Cornelia M, Kaprio, Jaakko, Cormand, Bru, Wessman, Maija, Frants, Rune R, Meitinger, Thomas, Müller-Myhsok, Bertram, Zwart, John-Anker, Färkkilä, Markus, Macaya, Alfons, Ferrari, Michel D, Kubisch, Christian, Palotie, Aarno, Dichgans, Martin, van den Maagdenberg, Arn MJM
Publicado em 2013

Genome-wide association analysis identifies susceptibility loci for migraine without aura

Por Freilinger, Tobias, Anttila, Verneri, de Vries, Boukje, Malik, Rainer, Kallela, Mikko, Terwindt, Gisela M, Pozo-Rosich, Patricia, Winsvold, Bendik, Nyholt, Dale R, van Oosterhout, Willebrordus P J, Artto, Ville, Todt, Unda, Hämäläinen, Eija, Fernández-Morales, Jèssica, Louter, Mark A, Kaunisto, Mari A, Schoenen, Jean, Raitakari, Olli, Lehtimäki, Terho, Vila-Pueyo, Marta, Göbel, Hartmut, Wichmann, Erich, Sintas, Cèlia, Uitterlinden, Andre G, Hofman, Albert, Rivadeneira, Fernando, Heinze, Axel, Tronvik, Erling, van Duijn, Cornelia M., Kaprio, Jaakko, Cormand, Bru, Wessman, Maija, Frants, Rune R, Meitinger, Thomas, Müller-Myhsok, Bertram, Zwart, John-Anker, Färkkilä, Markus, Macaya, Alfons, Ferrari, Michel D, Kubisch, Christian, Palotie, Aarno, Dichgans, Martin, van den Maagdenberg, Arn M J M
Publicado em 2012

Quantifying the Impact of Rare and Ultra-rare Coding Variation across the Phenotypic Spectrum

Por Ganna, Andrea, Satterstrom, F. Kyle, Zekavat, Seyedeh M., Das, Indraniel, Kurki, Mitja I., Churchhouse, Claire, Alfoldi, Jessica, Martin, Alicia R., Havulinna, Aki S., Byrnes, Andrea, Thompson, Wesley K., Nielsen, Philip R., Karczewski, Konrad J., Saarentaus, Elmo, Rivas, Manuel A., Gupta, Namrata, Pietiläinen, Olli, Emdin, Connor A., Lescai, Francesco, Bybjerg-Grauholm, Jonas, Flannick, Jason, Mercader, Josep M., Udler, Miriam, Laakso, Markku, Salomaa, Veikko, Hultman, Christina, Ripatti, Samuli, Hämäläinen, Eija, Moilanen, Jukka S., Körkkö, Jarmo, Kuismin, Outi, Nordentoft, Merete, Hougaard, David M., Mors, Ole, Werge, Thomas, Mortensen, Preben Bo, MacArthur, Daniel, Daly, Mark J., Sullivan, Patrick F., Locke, Adam E., Palotie, Aarno, Børglum, Anders D., Kathiresan, Sekar, Neale, Benjamin M.
Publicado no Am J Hum Genet (2018)

Pitfalls in genetic testing: the story of missed SCN1A mutations

Por Djémié, Tania, Weckhuysen, Sarah, von Spiczak, Sarah, Carvill, Gemma L., Jaehn, Johanna, Anttonen, Anna‐Kaisa, Brilstra, Eva, Caglayan, Hande S., de Kovel, Carolien G., Depienne, Christel, Gaily, Eija, Gennaro, Elena, Giraldez, Beatriz G., Gormley, Padhraig, Guerrero‐López, Rosa, Guerrini, Renzo, Hämäläinen, Eija, Hartmann, Corinna, Hernandez‐Hernandez, Laura, Hjalgrim, Helle, Koeleman, Bobby P. C., Leguern, Eric, Lehesjoki, Anna‐Elina, Lemke, Johannes R., Leu, Costin, Marini, Carla, McMahon, Jacinta M., Mei, Davide, Møller, Rikke S., Muhle, Hiltrud, Myers, Candace T., Nava, Caroline, Serratosa, Jose M., Sisodiya, Sanjay M., Stephani, Ulrich, Striano, Pasquale, van Kempen, Marjan J. A., Verbeek, Nienke E., Usluer, Sunay, Zara, Federico, Palotie, Aarno, Mefford, Heather C., Scheffer, Ingrid E., De Jonghe, Peter, Helbig, Ingo, Suls, Arvid
Publicado no Mol Genet Genomic Med (2016)

Distribution and Medical Impact of Loss-of-Function Variants in the Finnish Founder Population

Por Lim, Elaine T., Würtz, Peter, Havulinna, Aki S., Palta, Priit, Tukiainen, Taru, Rehnström, Karola, Esko, Tõnu, Mägi, Reedik, Inouye, Michael, Lappalainen, Tuuli, Chan, Yingleong, Salem, Rany M., Lek, Monkol, Flannick, Jason, Sim, Xueling, Manning, Alisa, Ladenvall, Claes, Bumpstead, Suzannah, Hämäläinen, Eija, Aalto, Kristiina, Maksimow, Mikael, Salmi, Marko, Blankenberg, Stefan, Ardissino, Diego, Shah, Svati, Horne, Benjamin, McPherson, Ruth, Hovingh, Gerald K., Reilly, Muredach P., Watkins, Hugh, Goel, Anuj, Farrall, Martin, Girelli, Domenico, Reiner, Alex P., Stitziel, Nathan O., Kathiresan, Sekar, Gabriel, Stacey, Barrett, Jeffrey C., Lehtimäki, Terho, Laakso, Markku, Groop, Leif, Kaprio, Jaakko, Perola, Markus, McCarthy, Mark I., Boehnke, Michael, Altshuler, David M., Lindgren, Cecilia M., Hirschhorn, Joel N., Metspalu, Andres, Freimer, Nelson B., Zeller, Tanja, Jalkanen, Sirpa, Koskinen, Seppo, Raitakari, Olli, Durbin, Richard, MacArthur, Daniel G., Salomaa, Veikko, Ripatti, Samuli, Daly, Mark J., Palotie, Aarno
Publicado em 2014

Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1

Por Anttila, Verneri, Stefansson, Hreinn, Kallela, Mikko, Todt, Unda, Terwindt, Gisela M, Calafato, M Stella, Nyholt, Dale R, Dimas, Antigone S, Freilinger, Tobias, Müller-Myhsok, Bertram, Artto, Ville, Inouye, Michael, Alakurtti, Kirsi, Kaunisto, Mari A, Hämäläinen, Eija, de Vries, Boukje, Stam, Anine H, Weller, Claudia M, Heinze, Axel, Heinze-Kuhn, Katja, Goebel, Ingrid, Borck, Guntram, Göbel, Hartmut, Steinberg, Stacy, Wolf, Christiane, Björnsson, Asgeir, Gudmundsson, Gretar, Kirchmann, Malene, Hauge, Anne, Werge, Thomas, Schoenen, Jean, Eriksson, Johan G, Hagen, Knut, Stovner, Lars, Wichmann, H-Erich, Meitinger, Thomas, Alexander, Michael, Moebus, Susanne, Schreiber, Stefan, Aulchenko, Yurii S, Breteler, Monique M B, Uitterlinden, Andre G, Hofman, Albert, van Duijn, Cornelia M, Tikka-Kleemola, Päivi, Vepsäläinen, Salli, Lucae, Susanne, Tozzi, Federica, Muglia, Pierandrea, Barrett, Jeffrey, Kaprio, Jaakko, Färkkilä, Markus, Peltonen, Leena, Stefansson, Kari, Zwart, John-Anker, Ferrari, Michel D, Olesen, Jes, Daly, Mark, Wessman, Maija, van den Maagdenberg, Arn M J M, Dichgans, Martin, Kubisch, Christian, Dermitzakis, Emmanouil T, Frants, Rune R, Palotie, Aarno
Publicado em 2010