Activation of MEK family kinases requires phosphorylation of two conserved Ser/Thr residues.

Por Zheng, C F, Guan, K L
Publicado em 1994

The kinase suppressor of Ras (KSR) modulates growth factor and Ras signaling by uncoupling Elk-1 phosphorylation from MAP kinase activation.

Por Sugimoto, T, Stewart, S, Han, M, Guan, K L
Publicado em 1998

The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis

Por Kang, Y J, Lu, M-K, Guan, K-L
Publicado em 2011

Regulation of Glycolysis and Gluconeogenesis by Acetylation of PKM and PEPCK

Por Xiong, Y., Lei, Q-Y., Zhao, S., Guan, K-L.
Publicado no Cold Spring Harb Symp Quant Biol (2011)

Tyrosine phosphate hydrolysis of host proteins by an essential Yersinia virulence determinant.

Por Bliska, J B, Guan, K L, Dixon, J E, Falkow, S
Publicado em 1991

Negative regulation of mitosis by two functionally overlapping PTPases in fission yeast.

Por Millar, J B, Russell, P, Dixon, J E, Guan, K L
Publicado em 1992

Nerve growth factor stimulates a novel protein kinase in PC-12 cells that phosphorylates and activates mitogen-activated protein kinase kinase (MEK).

Por Pang, L, Zheng, C F, Guan, K L, Saltiel, A R
Publicado em 1995

Cloning and expression of a protein-tyrosine-phosphatase.

Por Guan, K L, Haun, R S, Watson, S J, Geahlen, R L, Dixon, J E
Publicado em 1990

Isolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4.

Por Guan, K L, Jenkins, C W, Li, Y, O'Keefe, C L, Noh, S, Wu, X, Zariwala, M, Matera, A G, Xiong, Y
Publicado em 1996

Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation

Por Yang, H, Liu, Y, Bai, F, Zhang, J-Y, Ma, S-H, Liu, J, Xu, Z-D, Zhu, H-G, Ling, Z-Q, Ye, D, Guan, K-L, Xiong, Y
Publicado em 2012