Mechanism-Based Pharmacokinetic–Pharmacodynamic Modeling of the Dopamine D(2) Receptor Occupancy of Olanzapine in Rats

Por Johnson, Martin, Kozielska, Magdalena, Pilla Reddy, Venkatesh, Vermeulen, An, Li, Cheryl, Grimwood, Sarah, de Greef, Rik, Groothuis, Geny M. M., Danhof, Meindert, Proost, Johannes H.
Publicado em 2011

Pharmacokinetic-Pharmacodynamic Modeling of the D(2) and 5-HT(2A) Receptor Occupancy of Risperidone and Paliperidone in Rats

Por Kozielska, Magdalena, Johnson, Martin, Pilla Reddy, Venkatesh, Vermeulen, An, Li, Cheryl, Grimwood, Sarah, de Greef, Rik, Groothuis, Geny M. M., Danhof, Meindert, Proost, Johannes H.
Publicado em 2012

Application of cross-species PET imaging to assess neurotransmitter release in brain

Por Finnema, Sjoerd J., Scheinin, Mika, Shahid, Mohammed, Lehto, Jussi, Borroni, Edilio, Bang-Andersen, Benny, Sallinen, Jukka, Wong, Erik, Farde, Lars, Halldin, Christer, Grimwood, Sarah
Publicado no Psychopharmacology (Berl) (2015)

Erratum to: Translational Modeling in Schizophrenia: Predicting Human Dopamine D(2) Receptor Occupancy

Por Johnson, Martin, Kozielska, Magdalena, Pilla Reddy, Venkatesh, Vermeulen, An, Barton, Hugh A., Grimwood, Sarah, de Greef, Rik, Groothuis, Geny M. M., Danhof, Meindert, Proost, Johannes H.
Publicado no Pharm Res (2016)

Duration of Action of a Broad Range of Selective κ-Opioid Receptor Antagonists Is Positively Correlated with c-Jun N-Terminal Kinase-1 Activation

Por Melief, Erica J., Miyatake, Mayumi, Carroll, F. Ivy, Béguin, Cécile, Carlezon, William A., Cohen, Bruce M., Grimwood, Sarah, Mitch, Charles H., Rorick-Kehn, Linda, Chavkin, Charles
Publicado em 2011

Quantitative PK–PD Model-Based Translational Pharmacology of a Novel Kappa Opioid Receptor Antagonist Between Rats and Humans

Por Chang, Cheng, Byon, Wonkyung, Lu, Yifeng, Jacobsen, Leslie K., Badura, Lori L., Sawant-Basak, Aarti, Miller, Emily, Liu, Jing, Grimwood, Sarah, Wang, Ellen Q., Maurer, Tristan S.
Publicado em 2011

Characterization of [(11)C]Lu AE92686 as a PET radioligand for phosphodiesterase 10A in the nonhuman primate brain

Por Yang, Kai-Chun, Stepanov, Vladimir, Amini, Nahid, Martinsson, Stefan, Takano, Akihiro, Nielsen, Jacob, Bundgaard, Christoffer, Bang-Andersen, Benny, Grimwood, Sarah, Halldin, Christer, Farde, Lars, Finnema, Sjoerd J.
Publicado no Eur J Nucl Med Mol Imaging (2016)

Evaluation of the Agonist PET Radioligand [(11)C]GR103545 to Image Kappa Opioid Receptor in Humans: Kinetic Model Selection, Test-Retest Reproducibility and Receptor Occupancy by t...

Por Naganawa, Mika, Jacobsen, Leslie K., Zheng, Ming-Qiang, Lin, Shu-Fei, Banerjee, Anindita, Byon, Wonkyung, Weinzimmer, David, Tomasi, Giampaolo, Nabulsi, Nabeel, Grimwood, Sarah, Badura, Lori L., Carson, Richard E., McCarthy, Timothy J., Huang, Yiyun
Publicado em 2014

Amphetamine Decreases α(2C)-Adrenoceptor Binding of [(11)C]ORM-13070: A PET Study in the Primate Brain

Por Finnema, Sjoerd J, Hughes, Zoë A, Haaparanta-Solin, Merja, Stepanov, Vladimir, Nakao, Ryuji, Varnäs, Katarina, Varrone, Andrea, Arponen, Eveliina, Marjamäki, Päivi, Pohjanoksa, Katariina, Vuorilehto, Lauri, Babalola, Phebian A, Solin, Olof, Grimwood, Sarah, Sallinen, Jukka, Farde, Lars, Scheinin, Mika, Halldin, Christer
Publicado no Int J Neuropsychopharmacol (2015)