Improved protein splicing using embedded split inteins

door Gramespacher, Josef A., Stevens, Adam J., Thompson, Robert E., Muir, Tom W.
Gepubliceerd in Protein Sci (2018)

Proximity Induced Splicing Utilizing Caged Split Inteins

door Gramespacher, Josef A., Burton, Antony J., Guerra, Luis F., Muir, Tom W.
Gepubliceerd in J Am Chem Soc (2019)

An Atypical Mechanism of Split Intein Molecular Recognition and Folding

door Stevens, Adam J., Sekar, Giridhar, Gramespacher, Josef A., Cowburn, David, Muir, Tom W.
Gepubliceerd in J Am Chem Soc (2018)

Intein Zymogens: Conditional Assembly and Splicing of Split Inteins via Targeted Proteolysis

door Gramespacher, Josef A., Stevens, Adam J., Nguyen, Duy P., Chin, Jason W., Muir, Tom W.
Gepubliceerd in J Am Chem Soc (2017)

Development of Antibody-Based PROTACs for the Degradation of the Cell-Surface Immune Checkpoint Protein PD-L1

door Cotton, Adam D., Nguyen, Duy P., Gramespacher, Josef A., Seiple, Ian B., Wells, James A.
Gepubliceerd in J Am Chem Soc (2021)

Bispecific VH/Fab antibodies targeting neutralizing and non-neutralizing Spike epitopes demonstrate enhanced potency against SARS-CoV-2

door Lim, Shion A., Gramespacher, Josef A., Pance, Katarina, Rettko, Nicholas J., Solomon, Paige, Jin, Jing, Lui, Irene, Elledge, Susanna K., Liu, Jia, Bracken, Colton J., Simmons, Graham, Zhou, Xin X., Leung, Kevin K., Wells, James A.
Gepubliceerd in MAbs (2021)