Improved protein splicing using embedded split inteins

por Gramespacher, Josef A., Stevens, Adam J., Thompson, Robert E., Muir, Tom W.
Publicado en Protein Sci (2018)

Proximity Induced Splicing Utilizing Caged Split Inteins

por Gramespacher, Josef A., Burton, Antony J., Guerra, Luis F., Muir, Tom W.
Publicado en J Am Chem Soc (2019)

An Atypical Mechanism of Split Intein Molecular Recognition and Folding

por Stevens, Adam J., Sekar, Giridhar, Gramespacher, Josef A., Cowburn, David, Muir, Tom W.
Publicado en J Am Chem Soc (2018)

Intein Zymogens: Conditional Assembly and Splicing of Split Inteins via Targeted Proteolysis

por Gramespacher, Josef A., Stevens, Adam J., Nguyen, Duy P., Chin, Jason W., Muir, Tom W.
Publicado en J Am Chem Soc (2017)

Development of Antibody-Based PROTACs for the Degradation of the Cell-Surface Immune Checkpoint Protein PD-L1

por Cotton, Adam D., Nguyen, Duy P., Gramespacher, Josef A., Seiple, Ian B., Wells, James A.
Publicado en J Am Chem Soc (2021)

Bispecific VH/Fab antibodies targeting neutralizing and non-neutralizing Spike epitopes demonstrate enhanced potency against SARS-CoV-2

por Lim, Shion A., Gramespacher, Josef A., Pance, Katarina, Rettko, Nicholas J., Solomon, Paige, Jin, Jing, Lui, Irene, Elledge, Susanna K., Liu, Jia, Bracken, Colton J., Simmons, Graham, Zhou, Xin X., Leung, Kevin K., Wells, James A.
Publicado en MAbs (2021)