Molecular Mechanism of Action of Pharmacoperone Rescue of Misrouted GPCR Mutants: The GnRH Receptor

por Janovick, Jo Ann, Patny, Akshay, Mosley, Ralph, Goulet, Mark T., Altman, Michael D., Rush, Thomas S., Cornea, Anda, Conn, P. Michael
Publicado 2009

REFOLDING OF MISFOLDED MUTANT GPCR: POST-TRANSLATIONAL PHARMACOPERONE ACTION IN VITRO

por Janovick, Jo Ann, Brothers, Shaun P., Cornea, Anda, Bush, Eugene, Goulet, Mark T., Ashton, Wallace T., Sauer, Daryl R., Haviv, Fortuna, Greer, Jonathan, Conn, P. Michael
Publicado 2007

Structure-dependent Impairment of Intracellular Apolipoprotein E4 Trafficking and Its Detrimental Effects Are Rescued by Small-molecule Structure Correctors

por Brodbeck, Jens, McGuire, Jim, Liu, Zhaoping, Meyer-Franke, Anke, Balestra, Maureen E., Jeong, Dah-eun, Pleiss, Mike, McComas, Casey, Hess, Fred, Witter, David, Peterson, Scott, Childers, Matthew, Goulet, Mark, Liverton, Nigel, Hargreaves, Richard, Freedman, Stephen, Weisgraber, Karl H., Mahley, Robert W., Huang, Yadong
Publicado 2011

[(18)F]MK-9470, a positron emission tomography (PET) tracer for in vivo human PET brain imaging of the cannabinoid-1 receptor

por Burns, H. Donald, Van Laere, Koen, Sanabria-Bohórquez, Sandra, Hamill, Terence G., Bormans, Guy, Eng, Wai-si, Gibson, Ray, Ryan, Christine, Connolly, Brett, Patel, Shil, Krause, Stephen, Vanko, Amy, Van Hecken, Anne, Dupont, Patrick, De Lepeleire, Inge, Rothenberg, Paul, Stoch, S. Aubrey, Cote, Josee, Hagmann, William K., Jewell, James P., Lin, Linus S., Liu, Ping, Goulet, Mark T., Gottesdiener, Keith, Wagner, John A., de Hoon, Jan, Mortelmans, Luc, Fong, Tung M., Hargreaves, Richard J.
Publicado 2007