Neurodegeneration in Friedreich's Ataxia: From Defective Frataxin to Oxidative Stress

Por Gomes, Cláudio M., Santos, Renata
Publicado em 2013

Calcium dysregulation links ALS defective proteins and motor neuron selective vulnerability

Por Leal, Sónia S., Gomes, Cláudio M.
Publicado no Front Cell Neurosci (2015)

Metals and Neuronal Metal Binding Proteins Implicated in Alzheimer's Disease

Por Cristóvão, Joana S., Santos, Renata, Gomes, Cláudio M.
Publicado no Oxid Med Cell Longev (2016)

Neurodegeneration, Neurogenesis, and Oxidative Stress 2015

Por Santos, Renata, Bulteau, Anne-Laure, Gomes, Cláudio M.
Publicado no Oxid Med Cell Longev (2016)

Calcium Ions Promote Superoxide Dismutase 1 (SOD1) Aggregation into Non-fibrillar Amyloid: A LINK TO TOXIC EFFECTS OF CALCIUM OVERLOAD IN AMYOTROPHIC LATERAL SCLEROSIS (ALS)?

Por Leal, Sónia S., Cardoso, Isabel, Valentine, Joan S., Gomes, Cláudio M.
Publicado em 2013

Small Molecules Present in the Cerebrospinal Fluid Metabolome Influence Superoxide Dismutase 1 Aggregation

Por Cristóvão, Joana S., Leal, Sónia S., Cardoso, Isabel, Gomes, Cláudio M.
Publicado em 2013

Conformational stability of human frataxin and effect of Friedreich's ataxia-related mutations on protein folding

Por Correia, Ana R., Adinolfi, Salvatore, Pastore, Annalisa, Gomes, Cláudio M.
Publicado em 2006

Probing the Kinetic Stabilities of Friedreich’s Ataxia Clinical Variants Using a Solid Phase GroEL Chaperonin Capture Platform

Por Correia, Ana R., Naik, Subhashchandra, Fisher, Mark T., Gomes, Cláudio M.
Publicado no Biomolecules (2014)

Redox-linked transient deprotonation at the binuclear site in the aa(3)-type quinol oxidase from Acidianus ambivalens: Implications for proton translocation

Por Das, Tapan Kanti, Gomes, Cláudio M., Teixeira, Miguel, Rousseau, Denis L.
Publicado em 1999

Iron binding activity in yeast frataxin entails a trade off with stability in the α1/β1 acidic ridge region

Por Correia, Ana R., Wang, Tao, Craig, Elizabeth A., Gomes, Cláudio M.
Publicado em 2010

Functional control of the binuclear metal site in the metallo-β-lactamase-like fold by subtle amino acid replacements

Por Gomes, Cláudio M., Frazão, Carlos, Xavier, António V., Legall, Jean, Teixeira, Miguel
Publicado em 2002

The Sulfur Oxygenase Reductase from the Mesophilic Bacterium Halothiobacillus neapolitanus Is a Highly Active Thermozyme

Por Veith, Andreas, Botelho, Hugo M., Kindinger, Florian, Gomes, Cláudio M., Kletzin, Arnulf
Publicado em 2012

Protein Folding Modulates the Swapped Dimerization Mechanism of Methyl-Accepting Chemotaxis Heme Sensors

Por Silva, Marta A., Lucas, Tânia G., Salgueiro, Carlos A., Gomes, Cláudio M.
Publicado em 2012

Correction: Protein Folding Modulates the Swapped Dimerization Mechanism of Methyl-Accepting Chemotaxis Heme Sensors

Por Silva, Marta A., Lucas, Tânia G., Salgueiro, Carlos A., Gomes, Cláudio M.
Publicado em 2013

Neurodegeneration, Neurogenesis, and Oxidative Stress

Por Santos, Renata, Ruiz de Almodóvar, Carmen, Bulteau, Anne-Laure, Gomes, Cláudio M.
Publicado em 2013

Kinetic Analysis of L1 Homophilic Interaction: ROLE OF THE FIRST FOUR IMMUNOGLOBULIN DOMAINS AND IMPLICATIONS ON BINDING MECHANISM

Por Gouveia, Ricardo M., Gomes, Cláudio M., Sousa, Marcos, Alves, Paula M., Costa, Júlia
Publicado em 2008

Structural Requirements for VAP-B Oligomerization and Their Implication in Amyotrophic Lateral Sclerosis-associated VAP-B(P56S) Neurotoxicity

Por Kim, SoHui, Leal, Sónia S., Ben Halevy, Daniel, Gomes, Cláudio M., Lev, Sima
Publicado em 2010

High stability of a ferredoxin from the hyperthermophilic archaeon A. ambivalens: Involvement of electrostatic interactions and cofactors

Por Moczygemba, Charmaine, Guidry, Jesse, Jones, Kathryn L., Gomes, Cláudio M., Teixeira, Miguel, Wittung-Stafshede, Pernilla
Publicado em 2001

Intrinsically Disordered and Aggregation Prone Regions Underlie β-Aggregation in S100 Proteins

Por Carvalho, Sofia B., Botelho, Hugo M., Leal, Sónia S., Cardoso, Isabel, Fritz, Günter, Gomes, Cláudio M.
Publicado em 2013

A Conserved Cysteine Residue of Bacillus subtilis SpoIIIJ Is Important for Endospore Development

Por Côrte, Luísa, Valente, Filipa, Serrano, Mónica, Gomes, Cláudio M., Moran, Charles P., Henriques, Adriano O.
Publicado em 2014