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Probing the Kinetic Stabilities of Friedreich’s Ataxia Clinical Variants Using a Solid Phase GroEL Chaperonin Capture Platform

Numerous human diseases are caused by protein folding defects where the protein may become more susceptible to degradation or aggregation. Aberrant protein folding can affect the kinetic stability of the proteins even if these proteins appear to be soluble in vivo. Experimental discrimination betwee...

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Bibliografische gegevens
Gepubliceerd in:Biomolecules
Hoofdauteurs: Correia, Ana R., Naik, Subhashchandra, Fisher, Mark T., Gomes, Cláudio M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4279165/
https://ncbi.nlm.nih.gov/pubmed/25333765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom4040956
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