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Calcium dysregulation links ALS defective proteins and motor neuron selective vulnerability

More than 20 distinct gene loci have so far been implicated in amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder characterized by progressive neurodegeneration of motor neurons (MN) and death. Most of this distinct set of ALS-related proteins undergoes toxic deposition specific...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Leal, Sónia S., Gomes, Cláudio M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468822/
https://ncbi.nlm.nih.gov/pubmed/26136661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00225
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