Methylthioadenosine Suppresses Salmonella Virulence

by Bourgeois, Jeffrey S., Zhou, Daoguo, Thurston, Teresa L. M., Gilchrist, James J., Ko, Dennis C.
Published in Infect Immun (2018)

Cross-sectional study of IgG antibody levels to invasive nontyphoidal Salmonella LPS O-antigen with age in Uganda

by Stockdale, Lisa, Nalwoga, Angela, Nash, Stephen, Elias, Sean, Asiki, Gershim, Kusemererwa, Sylvia, Gilchrist, James J., Newton, Robert, MacLennan, Calman A.
Published in Gates Open Res (2019)

Risk of pneumococcal bacteremia in Kenyan children with glucose-6-phosphate dehydrogenase deficiency

by Gilchrist, James J., Uyoga, Sophie, Pirinen, Matti, Rautanen, Anna, Mwarumba, Salim, Njuguna, Patricia, Mturi, Neema, Hill, Adrian V. S., Scott, J. Anthony G., Williams, Thomas N.
Published in BMC Med (2020)

Sequential Acquisition of T Cells and Antibodies to Nontyphoidal Salmonella in Malawian Children

by Nyirenda, Tonney S., Gilchrist, James J., Feasey, Nicholas A., Glennie, Sarah J., Bar-Zeev, Naor, Gordon, Melita A., MacLennan, Calman A., Mandala, Wilson L., Heyderman, Robert S.
Published 2014

Genetic variation in VAC14 is associated with bacteremia secondary to diverse pathogens in African children

by Gilchrist, James J., Mentzer, Alexander J., Rautanen, Anna, Pirinen, Matti, Mwarumba, Salim, Njuguna, Patricia, Mturi, Neema, Williams, Thomas N., Scott, J. Anthony G., Hill, Adrian V. S.
Published in Proc Natl Acad Sci U S A (2018)

Genetic variants associated with non-typhoidal Salmonella bacteraemia in African children

by Gilchrist, James J, Mills, Tara C, Naranbhai, Vivek, Chapman, Stephen J, Fairfax, Benjamin P, Knight, Julian C, Williams, Thomas N, Scott, J Anthony G, MacLennan, Calman A, Rautanen, Anna, Hill, Adrian V
Published in Lancet (2015)

Cytokine Profiles during Invasive Nontyphoidal Salmonella Disease Predict Outcome in African Children

by Gilchrist, James J., Heath, Jennifer N., Msefula, Chisomo L., Gondwe, Esther N., Naranbhai, Vivek, Mandala, Wilson, MacLennan, Jenny M., Molyneux, Elizabeth M., Graham, Stephen M., Drayson, Mark T., Molyneux, Malcolm E., MacLennan, Calman A.
Published in Clin Vaccine Immunol (2016)

Lymphocyte Perturbations in Malawian Children with Severe and Uncomplicated Malaria

by Mandala, Wilson L., Msefula, Chisomo L., Gondwe, Esther N., Gilchrist, James J., Graham, Stephen M., Pensulo, Paul, Mwimaniwa, Grace, Banda, Meraby, Taylor, Terrie E., Molyneux, Elizabeth E., Drayson, Mark T., Ward, Steven A., Molyneux, Malcolm E., MacLennan, Calman A.
Published in Clin Vaccine Immunol (2016)

Presentation of life-threatening invasive nontyphoidal Salmonella disease in Malawian children: A prospective observational study

by MacLennan, Calman A., Msefula, Chisomo L., Gondwe, Esther N., Gilchrist, James J., Pensulo, Paul, Mandala, Wilson L., Mwimaniwa, Grace, Banda, Meraby, Kenny, Julia, Wilson, Lorna K., Phiri, Amos, MacLennan, Jenny M., Molyneux, Elizabeth M., Molyneux, Malcolm E., Graham, Stephen M.
Published in PLoS Negl Trop Dis (2017)

Human genetic and metabolite variation reveals that methylthioadenosine is a prognostic biomarker and an inflammatory regulator in sepsis

by Wang, Liuyang, Ko, Emily R., Gilchrist, James J., Pittman, Kelly J., Rautanen, Anna, Pirinen, Matti, Thompson, J. Will, Dubois, Laura G., Langley, Raymond J., Jaslow, Sarah L., Salinas, Raul E., Rouse, D. Clayburn, Moseley, M. Arthur, Mwarumba, Salim, Njuguna, Patricia, Mturi, Neema, Williams, Thomas N., Scott, J. Anthony G., Hill, Adrian V. S., Woods, Christopher W., Ginsburg, Geoffrey S., Tsalik, Ephraim L., Ko, Dennis C.
Published in Sci Adv (2017)

Risk of nontyphoidal Salmonella bacteraemia in African children is modified by STAT4

by Gilchrist, James J., Rautanen, Anna, Fairfax, Benjamin P., Mills, Tara C., Naranbhai, Vivek, Trochet, Holly, Pirinen, Matti, Muthumbi, Esther, Mwarumba, Salim, Njuguna, Patricia, Mturi, Neema, Msefula, Chisomo L., Gondwe, Esther N., MacLennan, Jenny M., Chapman, Stephen J., Molyneux, Malcolm E., Knight, Julian C., Spencer, Chris C. A., Williams, Thomas N., MacLennan, Calman A., Scott, J. Anthony G., Hill, Adrian V. S.
Published in Nat Commun (2018)

Dysregulated humoral immunity to nontyphoidal Salmonella in HIV-infected African adults

by MacLennan, Calman A., Gilchrist, James J., Gordon, Melita A., Cunningham, Adam F., Cobbold, Mark, Goodall, Margaret, Kingsley, Robert A., van Oosterhout, Joep J. G., Msefula, Chisomo L., Mandala, Wilson L., Leyton, Denisse L., Marshall, Jennifer L., Gondwe, Esther N., Bobat, Saeeda, López-Macías, Constantino, Doffinger, Rainer, Henderson, Ian R., Zijlstra, Eduard E., Dougan, Gordon, Drayson, Mark T., MacLennan, Ian C. M., Molyneux, Malcolm E.
Published 2010

The ferroportin Q248H mutation protects from anemia, but not malaria or bacteremia

by Muriuki, John Muthii, Mentzer, Alexander J., Band, Gavin, Gilchrist, James J., Carstensen, Tommy, Lule, Swaib A., Goheen, Morgan M., Joof, Fatou, Kimita, Wandia, Mogire, Reagan, Cutland, Clare L., Diarra, Amidou, Rautanen, Anna, Pomilla, Cristina, Gurdasani, Deepti, Rockett, Kirk, Mturi, Neema, Ndungu, Francis M., Scott, J. Anthony G., Sirima, Sodiomon B., Morovat, Alireza, Prentice, Andrew M., Madhi, Shabir A., Webb, Emily L., Elliott, Alison M., Bejon, Philip, Sandhu, Manjinder S., Hill, Adrian V. S., Kwiatkowski, Dominic P., Williams, Thomas N., Cerami, Carla, Atkinson, Sarah H.
Published in Sci Adv (2019)

Polymorphism in a lincRNA Associates with a Doubled Risk of Pneumococcal Bacteremia in Kenyan Children

by Rautanen, Anna, Pirinen, Matti, Mills, Tara C., Rockett, Kirk A., Strange, Amy, Ndungu, Anne W., Naranbhai, Vivek, Gilchrist, James J., Bellenguez, Céline, Freeman, Colin, Band, Gavin, Bumpstead, Suzannah J., Edkins, Sarah, Giannoulatou, Eleni, Gray, Emma, Dronov, Serge, Hunt, Sarah E., Langford, Cordelia, Pearson, Richard D., Su, Zhan, Vukcevic, Damjan, Macharia, Alex W., Uyoga, Sophie, Ndila, Carolyne, Mturi, Neema, Njuguna, Patricia, Mohammed, Shebe, Berkley, James A., Mwangi, Isaiah, Mwarumba, Salim, Kitsao, Barnes S., Lowe, Brett S., Morpeth, Susan C., Khandwalla, Iqbal, Blackwell, Jenefer M., Bramon, Elvira, Brown, Matthew A., Casas, Juan P., Corvin, Aiden, Duncanson, Audrey, Jankowski, Janusz, Markus, Hugh S., Mathew, Christopher G., Palmer, Colin N.A., Plomin, Robert, Sawcer, Stephen J., Trembath, Richard C., Viswanathan, Ananth C., Wood, Nicholas W., Deloukas, Panos, Peltonen, Leena, Williams, Thomas N., Scott, J. Anthony G., Chapman, Stephen J., Donnelly, Peter, Hill, Adrian V.S., Spencer, Chris C.A.
Published in Am J Hum Genet (2016)