Methods to Study Phase-Separated Condensates and the Underlying Molecular Interactions

Por Ganser, Laura R., Myong, Sua
Publicado no Trends Biochem Sci (2020)

HIV-1 leader RNA dimeric interface revealed by NMR

Por Ganser, Laura R., Al-Hashimi, Hashim M.
Publicado no Proc Natl Acad Sci U S A (2016)

An RNA tertiary switch by modifying how helices are tethered

Por Ganser, Laura R, Mustoe, Anthony M, Al-Hashimi, Hashim M
Publicado no Genome Biol (2014)

Development and Application of Aromatic [(13)C, (1)H] SOFAST-HMQC NMR Experiment for Nucleic Acids

Por Sathyamoorthy, Bharathwaj, Lee, Janghyun, Kimsey, Isaac, Ganser, Laura, Al-Hashimi, Hashim
Publicado no J Biomol NMR (2014)

The roles of structural dynamics in the cellular functions of RNAs

Por Ganser, Laura R., Kelly, Megan L., Herschlag, Daniel, Al-Hashimi, Hashim M.
Publicado no Nat Rev Mol Cell Biol (2019)

Resolving sugar puckers in RNA excited states exposes slow modes of repuckering dynamics

Por Clay, Mary C., Ganser, Laura R., Merriman, Dawn K., Al-Hashimi, Hashim M.
Publicado no Nucleic Acids Res (2017)

Demonstration that small molecules can bind and stabilize low-abundance short-lived RNA excited conformational states

Por Ganser, Laura R., Kelly, Megan L., Patwardhan, Neeraj N., Hargrove, Amanda E., Al-Hashimi, Hashim M.
Publicado no J Mol Biol (2019)

Probing RNA conformational equilibria within the functional cellular context

Por Ganser, Laura R., Chu, Chia-Chieh, Bogerd, Hal P., Kelly, Megan L., Cullen, Bryan R., Al-Hashimi, Hashim M.
Publicado no Cell Rep (2020)

Glucose Starvation Inhibits Autophagy via Vacuolar Hydrolysis and Induces Plasma Membrane Internalization by Down-regulating Recycling

Por Lang, Michael J., Martinez-Marquez, Jorge Y., Prosser, Derek C., Ganser, Laura R., Buelto, Destiney, Wendland, Beverly, Duncan, Mara C.
Publicado em 2014

Amiloride as a new RNA-binding scaffold with activity against HIV-1 TAR

Por Patwardhan, Neeraj N., Ganser, Laura R., Kapral, Gary J., Eubanks, Christopher S., Lee, Janghyun, Sathyamoorthy, Bharathwaj, Al-Hashimi, Hashim M., Hargrove, Amanda E.
Publicado no Medchemcomm (2017)

High Performance Virtual Screening by Targeting a High-resolution RNA Dynamic Ensemble

Por Ganser, Laura R., Lee, Janghyun, Rangadurai, Atul, Merriman, Dawn K., Kelly, Megan L., Kansal, Aman D., Sathyamoorthy, Bharathwaj, Al-Hashimi, Hashim M.
Publicado no Nat Struct Mol Biol (2018)

Understanding the characteristics of nonspecific binding of drug-like compounds to canonical stem–loop RNAs and their implications for functional cellular assays

Por Kelly, Megan L., Chu, Chia-Chieh, Shi, Honglue, Ganser, Laura R., Bogerd, Hal P., Huynh, Kelly, Hou, Yuze, Cullen, Bryan R., Al-Hashimi, Hashim M.
Publicado no RNA (2021)