How “precise” is precision medicine in hematology?

Por Gambacorti-Passerini, Carlo, Piazza, Rocco
Publicado no Haematologica (2017)

Synergistic Effects of Combined Wnt/KRAS Inhibition in Colorectal Cancer Cells

Por Mologni, Luca, Brussolo, Stefania, Ceccon, Monica, Gambacorti-Passerini, Carlo
Publicado em 2012

Activity of second-generation ALK inhibitors against crizotinib-resistant mutants in an NPM-ALK model compared to EML4-ALK

Por Fontana, Diletta, Ceccon, Monica, Gambacorti-Passerini, Carlo, Mologni, Luca
Publicado no Cancer Med (2015)

The Novel PIM1 Inhibitor NMS-P645 Reverses PIM1-Dependent Effects on TMPRSS2/ERG Positive Prostate Cancer Cells And Shows Anti-Proliferative Activity in Combination with PI3K Inhib...

Por Mologni, Luca, Magistroni, Vera, Casuscelli, Francesco, Montemartini, Marisa, Gambacorti-Passerini, Carlo
Publicado no J Cancer (2017)

Locking Src/Abl Tyrosine Kinase Activities Regulate Cell Differentiation and Invasion of Human Cervical Cancer Cells Expressing E6/E7 Oncoproteins of High-Risk HPV

Por Yasmeen, Amber, Alachkar, Amal, Dekhil, Hafedh, Gambacorti-Passerini, Carlo, Al Moustafa, Ala-Eddin
Publicado em 2010

FusionAnalyser: a new graphical, event-driven tool for fusion rearrangements discovery

Por Piazza, Rocco, Pirola, Alessandra, Spinelli, Roberta, Valletta, Simona, Redaelli, Sara, Magistroni, Vera, Gambacorti-Passerini, Carlo
Publicado em 2012

NPM/ALK mutants resistant to ASP3026 display variable sensitivity to alternative ALK inhibitors but succumb to the novel compound PF-06463922

Por Mologni, Luca, Ceccon, Monica, Pirola, Alessandra, Chiriano, Gianpaolo, Piazza, Rocco, Scapozza, Leonardo, Gambacorti-Passerini, Carlo
Publicado no Oncotarget (2015)

Dissection of the RET/β-catenin interaction in the TPC1 thyroid cancer cell line

Por Tartari, Carmen J, Donadoni, Carla, Manieri, Elisa, Mologni, Luca, Mina, Pamela Della, Villa, Antonello, Gambacorti-Passerini, Carlo
Publicado em 2011

BCR/ABL1 and BCR are under the transcriptional control of the MYC oncogene

Por Sharma, Nitesh, Magistroni, Vera, Piazza, Rocco, Citterio, Stefania, Mezzatesta, Caterina, Khandelwal, Praveen, Pirola, Alessandra, Gambacorti-Passerini, Carlo
Publicado no Mol Cancer (2015)

Synergistic activity of ALK and mTOR inhibitors for the treatment of NPM-ALK positive lymphoma

Por Redaelli, Sara, Ceccon, Monica, Antolini, Laura, Rigolio, Roberta, Pirola, Alessandra, Peronaci, Marco, Gambacorti-Passerini, Carlo, Mologni, Luca
Publicado no Oncotarget (2016)

hnRNP A1 Nucleocytoplasmic Shuttling Activity Is Required for Normal Myelopoiesis and BCR/ABL Leukemogenesis

Por Iervolino, Angela, Santilli, Giorgia, Trotta, Rossana, Guerzoni, Clara, Cesi, Vincenzo, Bergamaschi, Anna, Gambacorti-Passerini, Carlo, Calabretta, Bruno, Perrotti, Danilo
Publicado em 2002

Identification of novel point mutations in splicing sites integrating whole-exome and RNA-seq data in myeloproliferative diseases

Por Spinelli, Roberta, Pirola, Alessandra, Redaelli, Sara, Sharma, Nitesh, Raman, Hima, Valletta, Simona, Magistroni, Vera, Piazza, Rocco, Gambacorti-Passerini, Carlo
Publicado em 2013

Identification of novel point mutations in splicing sites integrating whole-exome and RNA-seq data in myeloproliferative diseases

Por Spinelli, Roberta, Pirola, Alessandra, Redaelli, Sara, Sharma, Nitesh, Raman, Hima, Valletta, Simona, Magistroni, Vera, Piazza, Rocco, Gambacorti-Passerini, Carlo
Publicado em 2014

In vitro and in vivo identification of ABCB1 as an efflux transporter of bosutinib

Por Redaelli, Sara, Perini, Pietro, Ceccon, Monica, Piazza, Rocco, Rigolio, Roberta, Mauri, Mario, Boschelli, Frank, Giannoudis, Athina, Gambacorti-Passerini, Carlo
Publicado no J Hematol Oncol (2015)

c-MYC Generates Repair Errors via Increased Transcription of Alternative-NHEJ Factors, LIG3 and PARP1, in Tyrosine Kinase-activated Leukemias

Por Muvarak, Nidal, Kelley, Shannon, Robert, Carine, Baer, Maria R., Perrotti, Danilo, Gambacorti-Passerini, Carlo, Civin, Curt, Scheibner, Kara, Rassool, Feyruz
Publicado no Mol Cancer Res (2015)

Bcr-Abl stabilizes β-catenin in chronic myeloid leukemia through its tyrosine phosphorylation

Por Coluccia, Addolorata Maria Luce, Vacca, Angelo, Duñach, Mireia, Mologni, Luca, Redaelli, Sara, Bustos, Victor H, Benati, Daniela, Pinna, Lorenzo A, Gambacorti-Passerini, Carlo
Publicado em 2007

CEQer: A Graphical Tool for Copy Number and Allelic Imbalance Detection from Whole-Exome Sequencing Data

Por Piazza, Rocco, Magistroni, Vera, Pirola, Alessandra, Redaelli, Sara, Spinelli, Roberta, Redaelli, Serena, Galbiati, Marta, Valletta, Simona, Giudici, Giovanni, Cazzaniga, Giovanni, Gambacorti-Passerini, Carlo
Publicado em 2013

Bosutinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukaemia: results from the 24-month follow-up of the BELA trial

Por Brümmendorf, Tim H, Cortes, Jorge E, de Souza, Cármino Antonio, Guilhot, Francois, Duvillié, Ladan, Pavlov, Dmitri, Gogat, Karïn, Countouriotis, Athena M, Gambacorti-Passerini, Carlo
Publicado no Br J Haematol (2015)

Sorafenib functions to potently suppress RET tyrosine kinase activity by direct enzymatic inhibition and promoting RET lysosomal degradation independent of proteasomal targeting.

Por Plaza-Menacho, Iván, Mologni, Luca, Sala, Elisa, Gambacorti-Passerini, Carlo, Magee, Anthony I., Links, Thera P., Hofstra, Robert M. W., Barford, David, Isacke, Clare M.
Publicado em 2009

ERG Deregulation Induces PIM1 Over-Expression and Aneuploidy in Prostate Epithelial Cells

Por Magistroni, Vera, Mologni, Luca, Sanselicio, Stefano, Reid, James Frances, Redaelli, Sara, Piazza, Rocco, Viltadi, Michela, Bovo, Giorgio, Strada, Guido, Grasso, Marco, Gariboldi, Manuela, Gambacorti-Passerini, Carlo
Publicado em 2011