Locking Src/Abl Tyrosine Kinase Activities Regulate Cell Differentiation and Invasion of Human Cervical Cancer Cells Expressing E6/E7 Oncoproteins of High-Risk HPV

In this study, we compared the effects of SKI-606 with Iressa, Src/Abl and EGF-R kinase inhibitors, respectively, on selected parameters in HeLa and SiHa cervical cancer cell lines, which express E6/E7 oncoproteins of high-risk HPV types 18 and 16, respectively. Our results show that SKI-606 and Ire...

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Detalhes bibliográficos
Main Authors: Yasmeen, Amber, Alachkar, Amal, Dekhil, Hafedh, Gambacorti-Passerini, Carlo, Al Moustafa, Ala-Eddin
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938462/
https://ncbi.nlm.nih.gov/pubmed/20862378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/530130
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