The TREX1 Exonuclease R114H Mutation in Aicardi-Goutières Syndrome and Lupus Reveals Dimeric Structure Requirements for DNA Degradation Activity

Por Orebaugh, Clinton D., Fye, Jason M., Harvey, Scott, Hollis, Thomas, Perrino, Fred W.
Publicado em 2011

Dominant Mutations of the TREX1 Exonuclease Gene in Lupus and Aicardi-Goutières Syndrome

Por Fye, Jason M., Orebaugh, Clinton D., Coffin, Stephanie R., Hollis, Thomas, Perrino, Fred W.
Publicado em 2011

The Arg-62 Residues of the TREX1 Exonuclease Act Across the Dimer Interface Contributing to Catalysis in the Opposing Protomers

Por Fye, Jason M., Coffin, Stephanie R., Orebaugh, Clinton D., Hollis, Thomas, Perrino, Fred W.
Publicado em 2014

The TREX1 C-terminal Region Controls Cellular Localization through Ubiquitination

Por Orebaugh, Clinton D., Fye, Jason M., Harvey, Scott, Hollis, Thomas, Wilkinson, John C., Perrino, Fred W.
Publicado em 2013

Exonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease

Por Grieves, Jessica L., Fye, Jason M., Harvey, Scott, Grayson, Jason M., Hollis, Thomas, Perrino, Fred W.
Publicado no Proc Natl Acad Sci U S A (2015)

Multifaceted role of TREX2 in the skin defense against UV-induced skin carcinogenesis

Por Manils, Joan, Gómez, Diana, Salla-Martret, Mercè, Fischer, Heinz, Fye, Jason M., Marzo, Elena, Marruecos, Laura, Serrano, Inma, Salgado, Rocío, Rodrigo, Juan P., Garcia-Pedrero, Juana M., Serafin, Anna M., Cañas, Xavier, Benito, Carmen, Toll, Agustí, Forcales, Sònia-Vanina, Perrino, Fred W., Eckhart, Leopold, Soler, Concepció
Publicado no Oncotarget (2015)