Binding of the Grb2 SH2 domain to phosphotyrosine motifs does not change the affinity of its SH3 domains for Sos proline-rich motifs.

Por Cussac, D, Frech, M, Chardin, P
Publicado em 1994

Validation of transgenic models of breast cancer: ductal carcinoma in situ (DCIS) and Brca1-mutation-related breast cancer

Por Frech, M. S., Jones, L. P., Furth, P. A.
Publicado em 2005

The inhibition of the GTPase activating protein-Ha-ras interaction by acidic lipids is due to physical association of the C-terminal domain of the GTPase activating protein with mi...

Por Serth, J, Lautwein, A, Frech, M, Wittinghofer, A, Pingoud, A
Publicado em 1991

Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: the C-terminal domain of GAP is not sufficient for full activity.

Por Gideon, P, John, J, Frech, M, Lautwein, A, Clark, R, Scheffler, J E, Wittinghofer, A
Publicado em 1992

Introduction of Estrogen Receptor-α into the tTA/TAg Conditional Mouse Model Precipitates the Development of Estrogen-Responsive Mammary Adenocarcinoma

Por Tilli, Maddalena T., Frech, M. Silvina, Steed, Mary E., Hruska, Kathleen S., Johnson, Michael D., Flaws, Jodi A., Furth, Priscilla A.
Publicado em 2003

Protein conformational flexibility modulates kinetics and thermodynamics of drug binding

Por Amaral, M., Kokh, D. B., Bomke, J., Wegener, A., Buchstaller, H. P., Eggenweiler, H. M., Matias, P., Sirrenberg, C., Wade, R. C., Frech, M.
Publicado no Nat Commun (2017)