Cellular adhesome screen identifies critical modulators of focal adhesion dynamics, cellular traction forces and cell migration behaviour

par Fokkelman, Michiel, Balcıoğlu, Hayri E., Klip, Janna E., Yan, Kuan, Verbeek, Fons J., Danen, Erik H. J., van de Water, Bob
Publié dans Sci Rep (2016)

High-Throughput Phenotypic Screening of Kinase Inhibitors to Identify Drug Targets for Polycystic Kidney Disease

par Booij, Tijmen H., Bange, Hester, Leonhard, Wouter N., Yan, Kuan, Fokkelman, Michiel, Kunnen, Steven J., Dauwerse, Johannes G., Qin, Yu, van de Water, Bob, van Westen, Gerard J. P., Peters, Dorien J. M., Price, Leo S.
Publié dans SLAS Discov (2017)

In vitro 3D phenotypic drug screen identifies celastrol as an effective in vivo inhibitor of polycystic kidney disease

par Booij, Tijmen H, Leonhard, Wouter N, Bange, Hester, Yan, Kuan, Fokkelman, Michiel, Plugge, Anna J, Veraar, Kimberley A M, Dauwerse, Johannes G, van Westen, Gerard J P, van de Water, Bob, Price, Leo S, Peters, Dorien J M
Publié dans J Mol Cell Biol (2019)

Migration rather than proliferation transcriptomic signatures are strongly associated with breast cancer patient survival

par Nair, Nishanth Ulhas, Das, Avinash, Rogkoti, Vasiliki-Maria, Fokkelman, Michiel, Marcotte, Richard, de Jong, Chiaro G., Koedoot, Esmee, Lee, Joo Sang, Meilijson, Isaac, Hannenhalli, Sridhar, Neel, Benjamin G., de Water, Bob van, Le Dévédec, Sylvia E., Ruppin, Eytan
Publié dans Sci Rep (2019)

Uncovering the signaling landscape controlling breast cancer cell migration identifies novel metastasis driver genes

par Koedoot, Esmee, Fokkelman, Michiel, Rogkoti, Vasiliki-Maria, Smid, Marcel, van de Sandt, Iris, de Bont, Hans, Pont, Chantal, Klip, Janna E., Wink, Steven, Timmermans, Mieke A., Wiemer, Erik A. C., Stoilov, Peter, Foekens, John A., Le Dévédec, Sylvia E., Martens, John W. M., van de Water, Bob
Publié dans Nat Commun (2019)