Phenylbutyrate increases activity of pyruvate dehydrogenase complex

door Ferriero, Rosa, Brunetti-Pierri, Nicola
Gepubliceerd in 2013

Differential inhibition of PDKs by phenylbutyrate and enhancement of pyruvate dehydrogenase complex activity by combination with dichloroacetate

door Ferriero, Rosa, Iannuzzi, Clara, Manco, Giuseppe, Brunetti-Pierri, Nicola
Gepubliceerd in J Inherit Metab Dis (2015)

Pyruvate dehydrogenase complex and lactate dehydrogenase are targets for therapy of acute liver failure

door Ferriero, Rosa, Nusco, Edoardo, De Cegli, Rossella, Carissimo, Annamaria, Manco, Giuseppe, Brunetti-Pierri, Nicola
Gepubliceerd in J Hepatol (2018)

Phenylbutyrate Therapy for Pyruvate Dehydrogenase Complex Deficiency and Lactic Acidosis

door Ferriero, Rosa, Manco, Giuseppe, Lamantea, Eleonora, Nusco, Edoardo, Ferrante, Mariella I., Sordino, Paolo, Stacpoole, Peter W., Lee, Brendan, Zeviani, Massimo, Brunetti-Pierri, Nicola
Gepubliceerd in 2013

Discovery of drug mode of action and drug repositioning from transcriptional responses

door Iorio, Francesco, Bosotti, Roberta, Scacheri, Emanuela, Belcastro, Vincenzo, Mithbaokar, Pratibha, Ferriero, Rosa, Murino, Loredana, Tagliaferri, Roberto, Brunetti-Pierri, Nicola, Isacchi, Antonella, di Bernardo, Diego
Gepubliceerd in 2010

CHOP and c-JUN up-regulate the mutant Z α(1)-antitrypsin, exacerbating its aggregation and liver proteotoxicity

door Attanasio, Sergio, Ferriero, Rosa, Gernoux, Gwladys, De Cegli, Rossella, Carissimo, Annamaria, Nusco, Edoardo, Campione, Severo, Teckman, Jeffrey, Mueller, Christian, Piccolo, Pasquale, Brunetti-Pierri, Nicola
Gepubliceerd in J Biol Chem (2020)

Phenylbutyrate increases pyruvate dehydrogenase complex activity in cells harboring a variety of defects

door Ferriero, Rosa, Boutron, Audrey, Brivet, Michele, Kerr, Douglas, Morava, Eva, Rodenburg, Richard J, Bonafé, Luisa, Baumgartner, Matthias R, Anikster, Yair, Braverman, Nancy E, Brunetti-Pierri, Nicola
Gepubliceerd in 2014

Up-regulation of miR-34b/c by JNK and FOXO3 protects from liver fibrosis

door Piccolo, Pasquale, Ferriero, Rosa, Barbato, Anna, Attanasio, Sergio, Monti, Marcello, Perna, Claudia, Borel, Florie, Annunziata, Patrizia, Carissimo, Annamaria, De Cegli, Rossella, Quagliata, Luca, Terracciano, Luigi M., Housset, Chantal, Teckman, Jeffrey H., Mueller, Christian, Brunetti-Pierri, Nicola
Gepubliceerd in Proc Natl Acad Sci U S A (2021)