Phenylbutyrate increases activity of pyruvate dehydrogenase complex

by Ferriero, Rosa, Brunetti-Pierri, Nicola
Published 2013

Differential inhibition of PDKs by phenylbutyrate and enhancement of pyruvate dehydrogenase complex activity by combination with dichloroacetate

by Ferriero, Rosa, Iannuzzi, Clara, Manco, Giuseppe, Brunetti-Pierri, Nicola
Published in J Inherit Metab Dis (2015)

Pyruvate dehydrogenase complex and lactate dehydrogenase are targets for therapy of acute liver failure

by Ferriero, Rosa, Nusco, Edoardo, De Cegli, Rossella, Carissimo, Annamaria, Manco, Giuseppe, Brunetti-Pierri, Nicola
Published in J Hepatol (2018)

Phenylbutyrate Therapy for Pyruvate Dehydrogenase Complex Deficiency and Lactic Acidosis

by Ferriero, Rosa, Manco, Giuseppe, Lamantea, Eleonora, Nusco, Edoardo, Ferrante, Mariella I., Sordino, Paolo, Stacpoole, Peter W., Lee, Brendan, Zeviani, Massimo, Brunetti-Pierri, Nicola
Published 2013

Discovery of drug mode of action and drug repositioning from transcriptional responses

by Iorio, Francesco, Bosotti, Roberta, Scacheri, Emanuela, Belcastro, Vincenzo, Mithbaokar, Pratibha, Ferriero, Rosa, Murino, Loredana, Tagliaferri, Roberto, Brunetti-Pierri, Nicola, Isacchi, Antonella, di Bernardo, Diego
Published 2010

CHOP and c-JUN up-regulate the mutant Z α(1)-antitrypsin, exacerbating its aggregation and liver proteotoxicity

by Attanasio, Sergio, Ferriero, Rosa, Gernoux, Gwladys, De Cegli, Rossella, Carissimo, Annamaria, Nusco, Edoardo, Campione, Severo, Teckman, Jeffrey, Mueller, Christian, Piccolo, Pasquale, Brunetti-Pierri, Nicola
Published in J Biol Chem (2020)

Phenylbutyrate increases pyruvate dehydrogenase complex activity in cells harboring a variety of defects

by Ferriero, Rosa, Boutron, Audrey, Brivet, Michele, Kerr, Douglas, Morava, Eva, Rodenburg, Richard J, Bonafé, Luisa, Baumgartner, Matthias R, Anikster, Yair, Braverman, Nancy E, Brunetti-Pierri, Nicola
Published 2014

Up-regulation of miR-34b/c by JNK and FOXO3 protects from liver fibrosis

by Piccolo, Pasquale, Ferriero, Rosa, Barbato, Anna, Attanasio, Sergio, Monti, Marcello, Perna, Claudia, Borel, Florie, Annunziata, Patrizia, Carissimo, Annamaria, De Cegli, Rossella, Quagliata, Luca, Terracciano, Luigi M., Housset, Chantal, Teckman, Jeffrey H., Mueller, Christian, Brunetti-Pierri, Nicola
Published in Proc Natl Acad Sci U S A (2021)