Geometric Attributes of Retaining Glycosyltransferase Enzymes Favor an Orthogonal Mechanism

Por Schuman, Brock, Evans, Stephen V., Fyles, Thomas M.
Publicado em 2013

Exploring the cross-reactivity of S25-2: complex with a 5,6-dehydro-Kdo disaccharide

Por Brooks, Cory L., Wimmer, Kurt, Kosma, Paul, Müller-Loennies, Sven, Brade, Lore, Brade, Helmut, Evans, Stephen V.
Publicado em 2012

Structural Basis for Antibody Recognition of Lipid A: INSIGHTS TO POLYSPECIFICITY TOWARD SINGLE-STRANDED DNA

Por Haji-Ghassemi, Omid, Müller-Loennies, Sven, Rodriguez, Teresa, Brade, Lore, Kosma, Paul, Brade, Helmut, Evans, Stephen V.
Publicado no J Biol Chem (2015)

The Combining Sites of Anti-lipid A Antibodies Reveal a Widely Utilized Motif Specific for Negatively Charged Groups

Por Haji-Ghassemi, Omid, Müller-Loennies, Sven, Rodriguez, Teresa, Brade, Lore, Grimmecke, Hans-Dieter, Brade, Helmut, Evans, Stephen V.
Publicado no J Biol Chem (2016)

Antibody WN1 222-5 mimics Toll-like receptor 4 binding in the recognition of LPS

Por Gomery, Kathryn, Müller-Loennies, Sven, Brooks, Cory L., Brade, Lore, Kosma, Paul, Di Padova, Franco, Brade, Helmut, Evans, Stephen V.
Publicado em 2012

Analysis of Cross-Reactive and Specific Anti-Carbohydrate Antibodies against Lipopolysaccharide from Chlamydophila psittaci: antibody / carbohydrate / Chlamydia / Kdo / LPS

Por Gerstenbruch, Sandra, Brooks, Cory L., Kosma, Paul, Brade, Lore, MacKenzie, C. Roger, Evans, Stephen V., Brade, Helmut, Müller-Loennies, Sven
Publicado em 2009

Cysteine-to-Serine Mutants Dramatically Reorder the Active Site of Human ABO(H) Blood Group B Glycosyltransferase without Affecting Activity: Structural Insights into Cooperative S...

Por Schuman, Brock, Persson, Mattias, Landry, Roxanne C., Polakowski, Robert, Weadge, Joel T., Seto, Nina O. L., Borisova, Svetlana N., Palcic, Monica M., Evans, Stephen V.
Publicado em 2010

Antibodies Raised Against Chlamydial Lipopolysaccharide Antigens Reveal Convergence in Germline Gene Usage and Differential Epitope Recognition

Por Brooks, Cory L, Müller-Loennies, Sven, Borisova, Svetlana N., Brade, Lore, Kosma, Paul, Hirama, Tomoko, MacKenzie, C. Roger, Brade, Helmut, Evans, Stephen V
Publicado em 2010

Groove-type Recognition of Chlamydiaceae-specific Lipopolysaccharide Antigen by a Family of Antibodies Possessing an Unusual Variable Heavy Chain N-Linked Glycan

Por Haji-Ghassemi, Omid, Müller-Loennies, Sven, Saldova, Radka, Muniyappa, Mohankumar, Brade, Lore, Rudd, Pauline M., Harvey, David J., Kosma, Paul, Brade, Helmut, Evans, Stephen V.
Publicado em 2014

High Resolution Structures of the Human ABO(H) Blood Group Enzymes in Complex with Donor Analogs Reveal That the Enzymes Utilize Multiple Donor Conformations to Bind Substrates in...

Por Gagnon, Susannah M. L., Meloncelli, Peter J., Zheng, Ruixiang B., Haji-Ghassemi, Omid, Johal, Asha R., Borisova, Svetlana N., Lowary, Todd L., Evans, Stephen V.
Publicado no J Biol Chem (2015)

Single-chain antibody-fragment M6P-1 possesses a mannose 6-phosphate monosaccharide-specific binding pocket that distinguishes N-glycan phosphorylation in a branch-specific manner(...

Por Blackler, Ryan J, Evans, Dylan W, Smith, David F, Cummings, Richard D, Brooks, Cory L, Braulke, Thomas, Liu, Xinyu, Evans, Stephen V, Müller-Loennies, Sven
Publicado no Glycobiology (2016)

High resolution structures of the human ABO(H) blood group enzymes in complex with donor analogs reveal that the enzymes utilize multiple donor conformations to bind substrates in...

Por Gagnon, Susannah M. L., Meloncelli, Peter J., Zheng, Ruixiang B., Haji-Ghassemi, Omid, Johal, Asha R., Borisova, Svetlana N., Lowary, Todd L., Evans, Stephen V.
Publicado no J Biol Chem (2016)

Antibody recognition of a unique tumor-specific glycopeptide antigen

Por Brooks, Cory L., Schietinger, Andrea, Borisova, Svetlana N., Kufer, Peter, Okon, Mark, Hirama, Tomoko, MacKenzie, C. Roger, Wang, Lai-Xi, Schreiber, Hans, Evans, Stephen V.
Publicado em 2010

Molecular Basis for Recognition of the Cancer Glycobiomarker, LacdiNAc (GalNAc[β1→4]GlcNAc), by Wisteria floribunda Agglutinin

Por Haji-Ghassemi, Omid, Gilbert, Michel, Spence, Jenifer, Schur, Melissa J., Parker, Matthew J., Jenkins, Meredith L., Burke, John E., van Faassen, Henk, Young, N. Martin, Evans, Stephen V.
Publicado no J Biol Chem (2016)

Structural basis of cell wall anchoring by SLH domains in Paenibacillus alvei

Por Blackler, Ryan J., López-Guzmán, Arturo, Hager, Fiona F., Janesch, Bettina, Martinz, Gudrun, Gagnon, Susannah M. L., Haji-Ghassemi, Omid, Kosma, Paul, Messner, Paul, Schäffer, Christina, Evans, Stephen V.
Publicado no Nat Commun (2018)

Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases(†)

Por Gagnon, Susannah M L, Legg, Max S G, Polakowski, Robert, Letts, James A, Persson, Mattias, Lin, Shuangjun, Zheng, Ruixiang Blake, Rempel, Brian, Schuman, Brock, Haji-Ghassemi, Omid, Borisova, Svetlana N, Palcic, Monica M, Evans, Stephen V
Publicado no Glycobiology (2018)