Hepatocellular carcinoma, novel therapies on the horizon

por El Dika, Imane, Makki, Iman, Abou-Alfa, Ghassan K.
Publicado en Chin Clin Oncol (2020)

Evolving treatment approaches for the management of metastatic castration-resistant prostate cancer – role of radium-223

por Mukherji, Deborah, El Dika, Imane, Temraz, Sally, Haidar, Mohammed, Shamseddine, Ali
Publicado 2014

Sunitinib Induced Thrombotic Thrombocytopenic Purpura in addition to Severe Hypothyroidism: A Case Report and Review of the Literature

por El Dika, Imane, Mukherji, Deborah, Temraz, Sally, Assi, Rita, Shamseddine, Ali
Publicado 2014

Leptomeningeal metastasis as initial manifestation of signet ring colorectal adenocarcinoma: a case report with review of literature

por Assi, Rita, Hamieh, Lana, Mukherji, Deborah, Haydar, Ali, Temraz, Sally, El-Dika, Imane, Shamseddine, Ali
Publicado en J Gastrointest Oncol (2015)

Maximizing response: a case report of salvage chemotherapy after immune checkpoint inhibition in a patient with previous chemo-refractory metastatic esophageal carcinoma

por Greally, Megan, Agarwal, Rajiv, El Dika, Imane, Shamseddine, Ali, El-Olayan, Ashwaq, Haibe, Yolla, Paroder, Viktoriya, Shia, Jinru, Abou-Alfa, Ghassan K., Ku, Geoffrey Y.
Publicado en J Gastrointest Oncol (2019)

A Phase Ib, Open‐Label Study of Dalantercept, an Activin Receptor‐Like Kinase 1 Ligand Trap, plus Sorafenib in Advanced Hepatocellular Carcinoma

por Abou‐Alfa, Ghassan K., Miksad, Rebecca A., Tejani, Mohamedtaki A., Williamson, Stephen, Gutierrez, Martin E., Olowokure, Olugbenga O., Sharma, Manish R., El Dika, Imane, Sherman, Matthew L., Pandya, Shuchi S.
Publicado en Oncologist (2018)

Phase II trial of sorafenib and doxorubicin in patients with advanced hepatocellular carcinoma after disease progression on sorafenib

por El Dika, Imane, Capanu, Marinela, Chou, Joanne F., Harding, James J., Ly, Michele, Hrabovsky, Anna D., Do, Richard K.G., Shia, Jinru, Millang, Brittanie, Ma, Jennifer, O’Reilly, Eileen M., Abou‐Alfa, Ghassan K.
Publicado en Cancer Med (2020)

A Multicenter Randomized Three‐Arm Phase II Study of (1) Everolimus, (2) Estrogen Deprivation Therapy (EDT) with Leuprolide + Letrozole, and (3) Everolimus + EDT in Patients with U...

por El Dika, Imane, Mayer, Robert J., Venook, Alan P., Capanu, Marinela, LaQuaglia, Michael P., Kobos, Rachel, O'Neill, Allison F., Chou, Joanne F., Ly, Michele, Ang, Celina, O'Reilly, Eileen M., Gordan, John D., Abou‐Alfa, Ghassan K.
Publicado en Oncologist (2020)

An Open‐Label, Multicenter, Phase I, Dose Escalation Study with Phase II Expansion Cohort to Determine the Safety, Pharmacokinetics, and Preliminary Antitumor Activity of Intraveno...

por El Dika, Imane, Lim, Ho Yeong, Yong, Wei Peng, Lin, Chia‐Chi, Yoon, Jung‐Hwan, Modiano, Manuel, Freilich, Bradley, Choi, Hye Jin, Chao, Tsu‐Yi, Kelley, Robin K., Brown, Joanne, Knox, Jennifer, Ryoo, Baek‐Yeol, Yau, Thomas, Abou‐Alfa, Ghassan K.
Publicado en Oncologist (2018)

Germline Alterations in Patients with Biliary Tract Cancers: A Spectrum of Significant and Previously Under Appreciated Findings

por Maynard, Hannah, Stadler, Zsofia K., Berger, Michael F., Solit, David B., Ly, Michele, Lowery, Maeve A., Mandelker, Diana, Zhang, Liying, Jordan, Emmett, El Dika, Imane, Kemel, Yelena, Ladanyi, Marc, Robson, Mark E., O’Reilly, Eileen M., Abou-Alfa, Ghassan K.
Publicado en Cancer (2020)

An elderly man with remote history of metastatic melanoma now with localized pancreas cancer and new liver masses

por Vasan, Neil, Braghiroli, Maria Ignez, Shoushtari, Alexander N., Do, Richard Kinh Gian, Edelweiss, Marcia, Shamseddine, Ali, Faraj, Walid, Mukherji, Deborah, Haydar, Ali, Olayan, Ashwaq, Sabatin, Fouad, Assi, Rita, El Dika, Imane, Saltz, Leonard B., Abou-Alfa, Ghassan K., O’Reilly, Eileen M.
Publicado en J Gastrointest Oncol (2017)

Phase Ib Study of Enzalutamide with or Without Sorafenib in Patients with Advanced Hepatocellular Carcinoma

por Harding, James J., Kelley, Robin K., Tan, Benjamin, Capanu, Marinela, Do, Gian Kinh, Shia, Jinru, Chou, Joanne F., Ferrer, Christine S., Boussayoud, Chayma, Muenkel, Kerri, Yarmohammadi, Hooman, El Dika, Imane, Khalil, Danny N., Ruiz, Carmen, Rodriguez‐Lee, Mariam, Kuhn, Peter, Wilton, John, Iyer, Renuka, Abou‐Alfa, Ghassan K.
Publicado en Oncologist (2020)

Discordant DNA mismatch repair protein status between synchronous or metachronous gastrointestinal carcinomas: frequency, patterns, and molecular etiologies

por Vyas, Monika, Firat, Canan, Hechtman, Jaclyn F., Weiser, Martin R., Yaeger, Rona, Vanderbilt, Chad, Benhamida, Jamal K., Keshinro, Ajaratu, Zhang, Liying, Ntiamoah, Peter, Gonzalez, Marco, Andrade, Rebecca, El Dika, Imane, Markowitz, Arnold J., Smith, J. Joshua, Garcia-Aguilar, Julio, Vakiani, Efsevia, Klimstra, David S., Stadler, Zsofia K., Shia, Jinru
Publicado en Fam Cancer (2020)

Comprehensive molecular profiling of intra- and extrahepatic cholangiocarcinomas: potential targets for intervention.

por Lowery, Maeve A., Ptashkin, Ryan, Jordan, Emmet, Berger, Michael F., Zehir, Ahmet, Capanu, Marinela, Kemeny, Nancy E., O’Reilly, Eileen M., El-Dika, Imane, Jarnagin, William R., Harding, James J., D’Angelica, Michael I., Cercek, Andrea, Hechtman, Jaclyn F., Solit, David B., Schultz, Nikolaus, Hyman, David M., Klimstra, David S., Saltz, Leonard B., Abou-Alfa, Ghassan K.
Publicado en Clin Cancer Res (2018)

Assessment of Treatment With Sorafenib Plus Doxorubicin vs Sorafenib Alone in Patients With Advanced Hepatocellular Carcinoma: Phase 3 CALGB 80802 Randomized Clinical Trial

por Abou-Alfa, Ghassan K., Shi, Qian, Knox, Jennifer J., Kaubisch, Andreas, Niedzwiecki, Donna, Posey, James, Tan, Benjamin R., Kavan, Petr, Goel, Rakesh, Lammers, Philip E., Bekaii-Saab, Tanios S., Tam, Vincent C., Rajdev, Lakshmi, Kelley, Robin K., El Dika, Imane, Zemla, Tyler, Potaracke, Ryan I., Balletti, Jennifer, El-Khoueiry, Anthony B., Harding, James J., Suga, Jennifer M., Schwartz, Lawrence H., Goldberg, Richard M., Bertagnolli, Monica M., Meyerhardt, Jeffrey, O’Reilly, Eileen M., Venook, Alan P.
Publicado en JAMA Oncol (2019)

Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection

por Park, Wungki, Chen, Jiapeng, Chou, Joanne F., Varghese, Anna, Yu, Kenneth, Wong, Winston, Capanu, Marinela, Balachandran, Vinod, McIntyre, Caitlin A., El Dika, Imane, Khalil, Danny N., Harding, James J., Ghalehsari, Nima, McKinell, Zoe, Chalasani, Sree, Makarov, Vladimir, Selenica, Pier, Pei, Xin, Lecomte, Nicolas, Kelsen, David, Abou-Alfa, Ghassan K., Robson, Mark E., Zhang, Liying, Berger, Michael F., Schultz, Nikolaus, Chan, Timothy A., Powell, Simon, Reis-Filho, Jorge S., Iacobuzio-Donahue, Christine A., Riaz, Nadeem, O’Reilly, Eileen M.
Publicado en Clin Cancer Res (2020)