Hepatocellular carcinoma, novel therapies on the horizon

by El Dika, Imane, Makki, Iman, Abou-Alfa, Ghassan K.
Published in Chin Clin Oncol (2020)

Evolving treatment approaches for the management of metastatic castration-resistant prostate cancer – role of radium-223

by Mukherji, Deborah, El Dika, Imane, Temraz, Sally, Haidar, Mohammed, Shamseddine, Ali
Published 2014

Sunitinib Induced Thrombotic Thrombocytopenic Purpura in addition to Severe Hypothyroidism: A Case Report and Review of the Literature

by El Dika, Imane, Mukherji, Deborah, Temraz, Sally, Assi, Rita, Shamseddine, Ali
Published 2014

Leptomeningeal metastasis as initial manifestation of signet ring colorectal adenocarcinoma: a case report with review of literature

by Assi, Rita, Hamieh, Lana, Mukherji, Deborah, Haydar, Ali, Temraz, Sally, El-Dika, Imane, Shamseddine, Ali
Published in J Gastrointest Oncol (2015)

Maximizing response: a case report of salvage chemotherapy after immune checkpoint inhibition in a patient with previous chemo-refractory metastatic esophageal carcinoma

by Greally, Megan, Agarwal, Rajiv, El Dika, Imane, Shamseddine, Ali, El-Olayan, Ashwaq, Haibe, Yolla, Paroder, Viktoriya, Shia, Jinru, Abou-Alfa, Ghassan K., Ku, Geoffrey Y.
Published in J Gastrointest Oncol (2019)

A Phase Ib, Open‐Label Study of Dalantercept, an Activin Receptor‐Like Kinase 1 Ligand Trap, plus Sorafenib in Advanced Hepatocellular Carcinoma

by Abou‐Alfa, Ghassan K., Miksad, Rebecca A., Tejani, Mohamedtaki A., Williamson, Stephen, Gutierrez, Martin E., Olowokure, Olugbenga O., Sharma, Manish R., El Dika, Imane, Sherman, Matthew L., Pandya, Shuchi S.
Published in Oncologist (2018)

Phase II trial of sorafenib and doxorubicin in patients with advanced hepatocellular carcinoma after disease progression on sorafenib

by El Dika, Imane, Capanu, Marinela, Chou, Joanne F., Harding, James J., Ly, Michele, Hrabovsky, Anna D., Do, Richard K.G., Shia, Jinru, Millang, Brittanie, Ma, Jennifer, O’Reilly, Eileen M., Abou‐Alfa, Ghassan K.
Published in Cancer Med (2020)

A Multicenter Randomized Three‐Arm Phase II Study of (1) Everolimus, (2) Estrogen Deprivation Therapy (EDT) with Leuprolide + Letrozole, and (3) Everolimus + EDT in Patients with U...

by El Dika, Imane, Mayer, Robert J., Venook, Alan P., Capanu, Marinela, LaQuaglia, Michael P., Kobos, Rachel, O'Neill, Allison F., Chou, Joanne F., Ly, Michele, Ang, Celina, O'Reilly, Eileen M., Gordan, John D., Abou‐Alfa, Ghassan K.
Published in Oncologist (2020)

An Open‐Label, Multicenter, Phase I, Dose Escalation Study with Phase II Expansion Cohort to Determine the Safety, Pharmacokinetics, and Preliminary Antitumor Activity of Intraveno...

by El Dika, Imane, Lim, Ho Yeong, Yong, Wei Peng, Lin, Chia‐Chi, Yoon, Jung‐Hwan, Modiano, Manuel, Freilich, Bradley, Choi, Hye Jin, Chao, Tsu‐Yi, Kelley, Robin K., Brown, Joanne, Knox, Jennifer, Ryoo, Baek‐Yeol, Yau, Thomas, Abou‐Alfa, Ghassan K.
Published in Oncologist (2018)

Germline Alterations in Patients with Biliary Tract Cancers: A Spectrum of Significant and Previously Under Appreciated Findings

by Maynard, Hannah, Stadler, Zsofia K., Berger, Michael F., Solit, David B., Ly, Michele, Lowery, Maeve A., Mandelker, Diana, Zhang, Liying, Jordan, Emmett, El Dika, Imane, Kemel, Yelena, Ladanyi, Marc, Robson, Mark E., O’Reilly, Eileen M., Abou-Alfa, Ghassan K.
Published in Cancer (2020)

An elderly man with remote history of metastatic melanoma now with localized pancreas cancer and new liver masses

by Vasan, Neil, Braghiroli, Maria Ignez, Shoushtari, Alexander N., Do, Richard Kinh Gian, Edelweiss, Marcia, Shamseddine, Ali, Faraj, Walid, Mukherji, Deborah, Haydar, Ali, Olayan, Ashwaq, Sabatin, Fouad, Assi, Rita, El Dika, Imane, Saltz, Leonard B., Abou-Alfa, Ghassan K., O’Reilly, Eileen M.
Published in J Gastrointest Oncol (2017)

Phase Ib Study of Enzalutamide with or Without Sorafenib in Patients with Advanced Hepatocellular Carcinoma

by Harding, James J., Kelley, Robin K., Tan, Benjamin, Capanu, Marinela, Do, Gian Kinh, Shia, Jinru, Chou, Joanne F., Ferrer, Christine S., Boussayoud, Chayma, Muenkel, Kerri, Yarmohammadi, Hooman, El Dika, Imane, Khalil, Danny N., Ruiz, Carmen, Rodriguez‐Lee, Mariam, Kuhn, Peter, Wilton, John, Iyer, Renuka, Abou‐Alfa, Ghassan K.
Published in Oncologist (2020)

Discordant DNA mismatch repair protein status between synchronous or metachronous gastrointestinal carcinomas: frequency, patterns, and molecular etiologies

by Vyas, Monika, Firat, Canan, Hechtman, Jaclyn F., Weiser, Martin R., Yaeger, Rona, Vanderbilt, Chad, Benhamida, Jamal K., Keshinro, Ajaratu, Zhang, Liying, Ntiamoah, Peter, Gonzalez, Marco, Andrade, Rebecca, El Dika, Imane, Markowitz, Arnold J., Smith, J. Joshua, Garcia-Aguilar, Julio, Vakiani, Efsevia, Klimstra, David S., Stadler, Zsofia K., Shia, Jinru
Published in Fam Cancer (2020)

Comprehensive molecular profiling of intra- and extrahepatic cholangiocarcinomas: potential targets for intervention.

by Lowery, Maeve A., Ptashkin, Ryan, Jordan, Emmet, Berger, Michael F., Zehir, Ahmet, Capanu, Marinela, Kemeny, Nancy E., O’Reilly, Eileen M., El-Dika, Imane, Jarnagin, William R., Harding, James J., D’Angelica, Michael I., Cercek, Andrea, Hechtman, Jaclyn F., Solit, David B., Schultz, Nikolaus, Hyman, David M., Klimstra, David S., Saltz, Leonard B., Abou-Alfa, Ghassan K.
Published in Clin Cancer Res (2018)

Assessment of Treatment With Sorafenib Plus Doxorubicin vs Sorafenib Alone in Patients With Advanced Hepatocellular Carcinoma: Phase 3 CALGB 80802 Randomized Clinical Trial

by Abou-Alfa, Ghassan K., Shi, Qian, Knox, Jennifer J., Kaubisch, Andreas, Niedzwiecki, Donna, Posey, James, Tan, Benjamin R., Kavan, Petr, Goel, Rakesh, Lammers, Philip E., Bekaii-Saab, Tanios S., Tam, Vincent C., Rajdev, Lakshmi, Kelley, Robin K., El Dika, Imane, Zemla, Tyler, Potaracke, Ryan I., Balletti, Jennifer, El-Khoueiry, Anthony B., Harding, James J., Suga, Jennifer M., Schwartz, Lawrence H., Goldberg, Richard M., Bertagnolli, Monica M., Meyerhardt, Jeffrey, O’Reilly, Eileen M., Venook, Alan P.
Published in JAMA Oncol (2019)

Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection

by Park, Wungki, Chen, Jiapeng, Chou, Joanne F., Varghese, Anna, Yu, Kenneth, Wong, Winston, Capanu, Marinela, Balachandran, Vinod, McIntyre, Caitlin A., El Dika, Imane, Khalil, Danny N., Harding, James J., Ghalehsari, Nima, McKinell, Zoe, Chalasani, Sree, Makarov, Vladimir, Selenica, Pier, Pei, Xin, Lecomte, Nicolas, Kelsen, David, Abou-Alfa, Ghassan K., Robson, Mark E., Zhang, Liying, Berger, Michael F., Schultz, Nikolaus, Chan, Timothy A., Powell, Simon, Reis-Filho, Jorge S., Iacobuzio-Donahue, Christine A., Riaz, Nadeem, O’Reilly, Eileen M.
Published in Clin Cancer Res (2020)