Model‐Informed Drug Development for Everolimus Dosing Selection in Pediatric Infant Patients

par Combes, Francois Pierre, Einolf, Heidi J., Coello, Neva, Heimbach, Tycho, He, Handan, Grosch, Kai
Publié dans CPT Pharmacometrics Syst Pharmacol (2020)

Cytochrome P450 1A2 Detoxicates Aristolochic Acid in the Mouse

par Rosenquist, Thomas A., Einolf, Heidi J., Dickman, Kathleen G., Wang, Lai, Smith, Amanda, Grollman, Arthur P.
Publié 2010

Drug Interaction Potential of Osilodrostat (LCI699) Based on Its Effect on the Pharmacokinetics of Probe Drugs of Cytochrome P450 Enzymes in Healthy Adults

par Armani, Sara, Ting, Lillian, Sauter, Nicholas, Darstein, Christelle, Tripathi, Anadya Prakash, Wang, Lai, Zhu, Bing, Gu, Helen, Chun, Dung Yu, Einolf, Heidi J, Kulkarni, Swarupa
Publié dans Clin Drug Investig (2017)

Physiologically Based Pharmacokinetic Model Qualification and Reporting Procedures for Regulatory Submissions: A Consortium Perspective

par Shebley, Mohamad, Sandhu, Punam, Emami Riedmaier, Arian, Jamei, Masoud, Narayanan, Rangaraj, Patel, Aarti, Peters, Sheila Annie, Reddy, Venkatesh Pilla, Zheng, Ming, de Zwart, Loeckie, Beneton, Maud, Bouzom, Francois, Chen, Jun, Chen, Yuan, Cleary, Yumi, Collins, Christiane, Dickinson, Gemma L., Djebli, Nassim, Einolf, Heidi J., Gardner, Iain, Huth, Felix, Kazmi, Faraz, Khalil, Feras, Lin, Jing, Odinecs, Aleksandrs, Patel, Chirag, Rong, Haojing, Schuck, Edgar, Sharma, Pradeep, Wu, Shu‐Pei, Xu, Yang, Yamazaki, Shinji, Yoshida, Kenta, Rowland, Malcolm
Publié dans Clin Pharmacol Ther (2018)