The phospho-dependent role of BRCA2 on the maintenance of chromosome integrity

by Ehlén, Åsa, Sessa, Gaetana, Zinn-Justin, Sophie, Carreira, Aura
Published in Cell Cycle (2021)

The Nuclear Localization of γ-Tubulin Is Regulated by SadB-mediated Phosphorylation

by Eklund, Greta, Lang, Stefan, Glindre, Johan, Ehlén, Åsa, Alvarado-Kristensson, Maria
Published 2014

A second DNA binding site in human BRCA2 promotes homologous recombination

by von Nicolai, Catharina, Ehlén, Åsa, Martin, Charlotte, Zhang, Xiaodong, Carreira, Aura
Published in Nat Commun (2016)

BRCA2 regulates DMC1-mediated recombination through the BRC repeats

by Martinez, Juan S., von Nicolai, Catharina, Kim, Taeho, Ehlén, Åsa, Mazin, Alexander V., Kowalczykowski, Stephen C., Carreira, Aura
Published in Proc Natl Acad Sci U S A (2016)

SRPK2 Promotes Leukemia Cell Proliferation by Phosphorylating Acinus and Regulating Cyclin A1

by Jang, Sung-Wuk, Yang, Seung-ju, Ehlén, Åsa, Dong, Shaozhong, Khoury, Hanna, Chen, Jing, Persson, Jenny L., Ye, Keqiang
Published 2008

Tumors with Nonfunctional Retinoblastoma Protein Are Killed by Reduced γ-Tubulin Levels

by Ehlén, Åsa, Rosselló, Catalina A., von Stedingk, Kristoffer, Höög, Greta, Nilsson, Elise, Pettersson, Helen M., Jirström, Karin, Alvarado-Kristensson, Maria
Published 2012

Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer

by Ehlén, Åsa, Brennan, Donal J, Nodin, Björn, O'Connor, Darran P, Eberhard, Jakob, Alvarado-Kristensson, Maria, Jeffrey, Ian B, Manjer, Jonas, Brändstedt, Jenny, Uhlén, Mathias, Pontén, Fredrik, Jirström, Karin
Published 2010

Functional assays for analysis of variants of uncertain significance in BRCA2

by Guidugli, Lucia, Carreira, Aura, Caputo, Sandrine M., Ehlen, Asa, Galli, Alvaro, Monteiro, Alvaro N.A., Neuhausen, Susan L., Hansen, Thomas V.O., Couch, Fergus J., Vreeswijk, Maaike P.G.
Published 2013

Proper chromosome alignment depends on BRCA2 phosphorylation by PLK1

by Ehlén, Åsa, Martin, Charlotte, Miron, Simona, Julien, Manon, Theillet, François-Xavier, Ropars, Virginie, Sessa, Gaetana, Beaurepere, Romane, Boucherit, Virginie, Duchambon, Patricia, El Marjou, Ahmed, Zinn-Justin, Sophie, Carreira, Aura
Published in Nat Commun (2020)

BRCA2 promotes DNA‐RNA hybrid resolution by DDX5 helicase at DNA breaks to facilitate their repair

by Sessa, Gaetana, Gómez‐González, Belén, Silva, Sonia, Pérez‐Calero, Carmen, Beaurepere, Romane, Barroso, Sonia, Martineau, Sylvain, Martin, Charlotte, Ehlén, Åsa, Martínez, Juan S, Lombard, Bérangère, Loew, Damarys, Vagner, Stephan, Aguilera, Andrés, Carreira, Aura
Published in EMBO J (2021)

Full in-frame exon 3 skipping of BRCA2 confers high risk of breast and/or ovarian cancer

by Caputo, Sandrine M., Léone, Mélanie, Damiola, Francesca, Ehlen, Asa, Carreira, Aura, Gaidrat, Pascaline, Martins, Alexandra, Brandão, Rita D., Peixoto, Ana, Vega, Ana, Houdayer, Claude, Delnatte, Capucine, Bronner, Myriam, Muller, Danièle, Castera, Laurent, Guillaud-Bataille, Marine, Søkilde, Inge, Uhrhammer, Nancy, Demontety, Sophie, Tubeuf, Hélène, Castelain, Gaïa, Jensen, Uffe Birk, Petitalot, Ambre, Krieger, Sophie, Lefol, Cédrick, Moncoutier, Virginie, Boutry-Kryza, Nadia, Nielsen, Henriette Roed, Sinilnikova, Olga, Stoppa-Lyonnet, Dominique, Spurdle, Amanda B., Teixeira, Manuel R., Coulet, Florence, Thomassen, Mads, Rouleau, Etienne
Published in Oncotarget (2018)

BRCA2 hypomorphic missense variants confer moderate risks of breast cancer

by Shimelis, Hermela, Mesman, Romy L.S., Von Nicolai, Catharina, Ehlen, Asa, Guidugli, Lucia, Martin, Charlotte, Calléja, Fabienne M.G.R., Meeks, Huong, Hallberg, Emily, Hinton, Jamie, Lilyquist, Jenna, Hu, Chunling, Aalfs, Cora M., Aittomäki, Kristiina, Andrulis, Irene, Anton-Culver, Hoda, Arndt, Volker, Beckmann, Matthias W., Benitez, Javier, Bogdanova, Natalia V., Bojesen, Stig E., Bolla, Manjeet K., Borresen-Dale, Anne-Lise, Brauch, Hiltrud, Brennan, Paul, Brenner, Hermann, Broeks, Annegien, Brouwers, Barbara, Brüning, Thomas, Burwinkel, Barbara, Chang-Claude, Jenny, Chenevix-Trench, Georgia, Cheng, Ching-Yu, Choi, Ji-Yeob, Collée, Margriet, Cox, Angela, Cross, Simon S., Czene, Kamila, Darabi, Hatef, Dennis, Joe, Dörk, Thilo, dos-Santos-Silva, Isabel, Dunning, Alison M., Fasching, Peter A., Figueroa, Jonine, Flyger, Henrik, García-Closas, Montserrat, Giles, Graham G., Glendon, Gord, Guénel, Pascal, Haiman, Christopher A., Hall, Per, Hamann, Ute, Hartman, Mikael, Hogervorst, Frans B., Hollestelle, Antoinette, Hopper, John L., Ito, Hidemi, Jakubowska, Anna, Kang, Daehee, Kosma, Veli-Matti, Kristensen, Vessela, Collaborators, for NBCS, Lai, Kah-Nyin, Lambrechts, Diether, Le Marchand, Loic, Li, Jingmei, Lindblom, Annika, Lophatananon, Artitaya, Lubinski, Jan, Machackova, Eva, Mannermaa, Arto, Margolin, Sara, Marme, Frederik, Matsuo, Keitaro, Miao, Hui, Michailidou, Kyriaki, Milne, Roger L., Muir, Kenneth, Neuhausen, Susan L., Nevanlinna, Heli, Olson, Janet E., Olswold, Curtis, Oosterwijk, Jan J.C., Osorio, Ana, Peterlongo, Paolo, Peto, Julian, Pharoah, Paul D.P., Pylkäs, Katri, Radice, Paolo, Rashid, Muhammad Usman, Rhenius, Valerie, Rudolph, Anja, Sangrajrang, Suleeporn, Sawyer, Elinor J., Schmidt, Marjanka K., Schoemaker, Minouk J., Seynaeve, Caroline, Shah, Mitul, Shen, Chen-Yang, Shrubsole, Martha, Shu, Xiao-Ou, Slager, Susan, Southey, Melissa C., Stram, Daniel O., Swerdlow, Anthony, Teo, Soo H., Tomlinson, Ian, Torres, Diana, Truong, Thérèse, van Asperen, Christi J., van der Kolk, Lizet E., Wang, Qin, Winqvist, Robert, Wu, Anna H., Yu, Jyh-Cherng, Zheng, Wei, Zheng, Ying, Leary, Jennifer, Walker, Logan, Foretova, Lenka, Fostira, Florentia, Claes, Kathleen B.M., Varesco, Liliana, Moghadasi, Setareh, Easton, Douglas F., Spurdle, Amanda, Devilee, Peter, Vrieling, Harry, Monteiro, Alvaro N.A., Goldgar, David E., Carreira, Aura, Vreeswijk, Maaike P.G., Couch, Fergus J.
Published in Cancer Res (2017)