Pulmonary pharmacodynamics of an anti-GM-CSFRα antibody enables therapeutic dosing that limits exposure in the lung

Por Campbell, Jamie, Nys, Josquin, Eghobamien, Laura, Cohen, E. Suzanne, Robinson, Matthew J., Sleeman, Matthew A.
Publicado no MAbs (2016)

Haplosaurus computes protein haplotypes for use in precision drug design

Por Spooner, William, McLaren, William, Slidel, Timothy, Finch, Donna K., Butler, Robin, Campbell, Jamie, Eghobamien, Laura, Rider, David, Kiefer, Christine Mione, Robinson, Matthew J., Hardman, Colin, Cunningham, Fiona, Vaughan, Tristan, Flicek, Paul, Huntington, Catherine Chaillan
Publicado no Nat Commun (2018)

Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors

Por Colley, Caroline S., Popovic, Bojana, Sridharan, Sudharsan, Debreczeni, Judit E., Hargeaves, David, Fung, Michael, An, Ling–Ling, Edwards, Bryan, Arnold, Joanne, England, Elizabeth, Eghobamien, Laura, Sivars, Ulf, Flavell, Liz, Renshaw, Jonathan, Wickson, Kate, Warrener, Paul, Zha, Jingying, Bonnell, Jessica, Woods, Rob, Wilkinson, Trevor, Dobson, Claire, Vaughan, Tristan J.
Publicado no MAbs (2017)