Haplosaurus computes protein haplotypes for use in precision drug design

Selecting the most appropriate protein sequences is critical for precision drug design. Here we describe Haplosaurus, a bioinformatic tool for computation of protein haplotypes. Haplosaurus computes protein haplotypes from pre-existing chromosomally-phased genomic variation data. Integration into th...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Spooner, William, McLaren, William, Slidel, Timothy, Finch, Donna K., Butler, Robin, Campbell, Jamie, Eghobamien, Laura, Rider, David, Kiefer, Christine Mione, Robinson, Matthew J., Hardman, Colin, Cunningham, Fiona, Vaughan, Tristan, Flicek, Paul, Huntington, Catherine Chaillan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175845/
https://ncbi.nlm.nih.gov/pubmed/30297836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06542-1
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