Discovery of Potent and Orally Bioavailable Small Molecule Antagonists of Toll-like Receptors 7/8/9 (TLR7/8/9)

af Mussari, Christopher P., Dodd, Dharmpal S., Sreekantha, Ratna Kumar, Pasunoori, Laxman, Wan, Honghe, Posy, Shana L., Critton, David, Ruepp, Stefan, Subramanian, Murali, Watson, Andrew, Davies, Paul, Schieven, Gary L., Salter-Cid, Luisa M., Srivastava, Ratika, Tagore, Debarati Mazumder, Dudhgaonkar, Shailesh, Poss, Michael A., Carter, Percy H., Dyckman, Alaric J.
Udgivet i ACS Med Chem Lett (2020)

Aryl Ether-Derived Sphingosine-1-Phosphate Receptor (S1P(1)) Modulators: Optimization of the PK, PD, and Safety Profiles

af Xiao, Zili, Yang, Michael G., Dhar, T. G. Murali, Xiao, Hai-Yun, Gilmore, John L., Marcoux, David, McIntyre, Kim W., Taylor, Tracy L., Shi, Hong, Levesque, Paul C., Marino, Anthony M., Cornelius, Georgia, Mathur, Arvind, Shen, Ding Ren, Cvijic, Mary Ellen, Lehman-McKeeman, Lois D., Sun, Huadong, Xie, Jenny H., Carter, Percy H., Dyckman, Alaric J.
Udgivet i ACS Med Chem Lett (2020)

Identification and Preclinical Pharmacology of BMS-986104: A Differentiated S1P(1) Receptor Modulator in Clinical Trials

af Dhar, T. G. Murali, Xiao, Hai-Yun, Xie, Jenny, Lehman-McKeeman, Lois D., Wu, Dauh-Rurng, Dabros, Marta, Yang, Xiaoxia, Taylor, Tracy L., Zhou, Xia D., Heimrich, Elizabeth M., Thomas, Rochelle, McIntyre, Kim W., Warrack, Bethanne, Shi, Hong, Levesque, Paul C., Zhu, Jia L., Hennan, James, Balimane, Praveen, Yang, Zheng, Marino, Anthony M., Cornelius, Georgia, D’Arienzo, Celia J., Mathur, Arvind, Shen, Ding Ren, Cvijic, Mary Ellen, Salter-Cid, Luisa, Barrish, Joel C., Carter, Percy H., Dyckman, Alaric J.
Udgivet i ACS Med Chem Lett (2016)

Identification of potent tricyclic prodrug S1P(1) receptor modulators

af Marcoux, David, Xiao, Hai-Yun, Murali Dhar, T. G., Xie, Jenny, Lehman-McKeeman, Lois D., Wu, Dauh-Rurng, Dabros, Marta, Yang, Xiaoxia, Taylor, Tracy L., Zhou, Xia D., Heimrich, Elizabeth M., Thomas, Rochelle, McIntyre, Kim W., Shi, Hong, Levesque, Paul C., Sun, Huadong, Yang, Zheng, Marino, Anthony M., Cornelius, Georgia, D'Arienzo, Celia J., Gupta, Anuradha, Pragalathan, Bala, Rampulla, Richard, Mathur, Arvind, Shen, Ding Ren, Cvijic, Mary Ellen, Salter-Cid, Luisa, Lombardo, Louis J., Carter, Percy H., Dyckman, Alaric J.
Udgivet i Medchemcomm (2016)