Identifying Causal Genes at the Multiple Sclerosis Associated Region 6q23 Using Capture Hi-C

Autor Martin, Paul, McGovern, Amanda, Massey, Jonathan, Schoenfelder, Stefan, Duffus, Kate, Yarwood, Annie, Barton, Anne, Worthington, Jane, Fraser, Peter, Eyre, Stephen, Orozco, Gisela
Vydáno v PLoS One (2016)

Chromatin interactions reveal novel gene targets for drug repositioning in rheumatic diseases

Autor Martin, Paul, Ding, James, Duffus, Kate, Gaddi, Vasanthi Priyadarshini, McGovern, Amanda, Ray-Jones, Helen, Yarwood, Annie, Worthington, Jane, Barton, Anne, Orozco, Gisela
Vydáno v Ann Rheum Dis (2019)

Analysis of chromatin organization and gene expression in T cells identifies functional genes for rheumatoid arthritis

Autor Yang, Jing, McGovern, Amanda, Martin, Paul, Duffus, Kate, Ge, Xiangyu, Zarrineh, Peyman, Morris, Andrew P., Adamson, Antony, Fraser, Peter, Rattray, Magnus, Eyre, Stephen
Vydáno v Nat Commun (2020)

Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci

Autor Martin, Paul, McGovern, Amanda, Orozco, Gisela, Duffus, Kate, Yarwood, Annie, Schoenfelder, Stefan, Cooper, Nicholas J., Barton, Anne, Wallace, Chris, Fraser, Peter, Worthington, Jane, Eyre, Steve
Vydáno v Nat Commun (2015)

Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits

Autor Shi, Chenfu, Ray-Jones, Helen, Ding, James, Duffus, Kate, Fu, Yao, Gaddi, Vasanthi Priyadarshini, Gough, Oliver, Hankinson, Jenny, Martin, Paul, McGovern, Amanda, Yarwood, Annie, Gaffney, Patrick, Eyre, Steve, Rattray, Magnus, Warren, Richard B., Orozco, Gisela
Vydáno v J Invest Dermatol (2021)

Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23

Autor McGovern, Amanda, Schoenfelder, Stefan, Martin, Paul, Massey, Jonathan, Duffus, Kate, Plant, Darren, Yarwood, Annie, Pratt, Arthur G., Anderson, Amy E., Isaacs, John D., Diboll, Julie, Thalayasingam, Nishanthi, Ospelt, Caroline, Barton, Anne, Worthington, Jane, Fraser, Peter, Eyre, Stephen, Orozco, Gisela
Vydáno v Genome Biol (2016)

Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31

Autor Ray-Jones, Helen, Duffus, Kate, McGovern, Amanda, Martin, Paul, Shi, Chenfu, Hankinson, Jenny, Gough, Oliver, Yarwood, Annie, Morris, Andrew P., Adamson, Antony, Taylor, Christopher, Ding, James, Gaddi, Vasanthi Priyadarshini, Fu, Yao, Gaffney, Patrick, Orozco, Gisela, Warren, Richard B., Eyre, Steve
Vydáno v BMC Biol (2020)

Replication of Associations of Genetic Loci Outside the HLA Region With Susceptibility to Anti–Cyclic Citrullinated Peptide–Negative Rheumatoid Arthritis

Autor Viatte, Sebastien, Massey, Jonathan, Bowes, John, Duffus, Kate, Eyre, Stephen, Barton, Anne, Worthington, Jane, Loughlin, John, Arden, Nigel, Birrell, Fraser, Carr, Andrew, Deloukas, Panos, Doherty, Michael, McCaskie, Andrew W., Ollier, William E. R., Rai, Ashok, Ralston, Stuart H., Spector, Tim D., Valdes, Ana M., Wallis, Gillian A., Wilkinson, J. Mark, Zeggini, Eleftheria
Vydáno v Arthritis Rheumatol (2016)