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Analysis of chromatin organization and gene expression in T cells identifies functional genes for rheumatoid arthritis

Genome-wide association studies have identified genetic variation contributing to complex disease risk. However, assigning causal genes and mechanisms has been more challenging because disease-associated variants are often found in distal regulatory regions with cell-type specific behaviours. Here,...

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書目詳細資料
發表在:Nat Commun
Main Authors: Yang, Jing, McGovern, Amanda, Martin, Paul, Duffus, Kate, Ge, Xiangyu, Zarrineh, Peyman, Morris, Andrew P., Adamson, Antony, Fraser, Peter, Rattray, Magnus, Eyre, Stephen
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7468106/
https://ncbi.nlm.nih.gov/pubmed/32879318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18180-7
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