The use of mechanistic DM-PK-PD modelling to assess the power of pharmacogenetic studies –CYP2C9 and warfarin as an example

Por Dickinson, Gemma L, Lennard, Martin S, Tucker, Geoffrey T, Rostami-Hodjegan, Amin
Publicado em 2007

Receptor Occupancy of the κ-Opioid Antagonist LY2456302 Measured with Positron Emission Tomography and the Novel Radiotracer (11)C-LY2795050

Por Naganawa, Mika, Dickinson, Gemma L., Zheng, Ming-Qiang, Henry, Shannan, Vandenhende, Francois, Witcher, Jennifer, Bell, Robert, Nabulsi, Nabeel, Lin, Shu-Fei, Ropchan, Jim, Neumeister, Alexander, Ranganathan, Mohini, Tauscher, Johannes, Huang, Yiyun, Carson, Richard E.
Publicado no J Pharmacol Exp Ther (2016)