Pharmacodynamic Evidence that Ciprofloxacin Failure against Tuberculosis Is Not Due to Poor Microbial Kill but to Rapid Emergence of Resistance

Por Gumbo, Tawanda, Louie, Arnold, Deziel, Mark R., Drusano, George L.
Publicado em 2005

Impact of Resistance Selection and Mutant Growth Fitness on the Relative Efficacies of Streptomycin and Levofloxacin for Plague Therapy

Por Louie, Arnold, Deziel, Mark R., Liu, Weiguo, Drusano, George L.
Publicado em 2007

The Relationship between Quinolone Exposures and Resistance Amplification Is Characterized by an Inverted U: a New Paradigm for Optimizing Pharmacodynamics To Counterselect Resista...

Por Tam, Vincent H., Louie, Arnold, Deziel, Mark R., Liu, Weiguo, Drusano, George L.
Publicado em 2007

Pharmacodynamics of Cidofovir for Vaccinia Virus Infection in an In Vitro Hollow-Fiber Infection Model System

Por McSharry, James J., Deziel, Mark R., Zager, Kris, Weng, Qingmei, Drusano, George L.
Publicado em 2009

In Vitro Infection Model Characterizing the Effect of Efflux Pump Inhibition on Prevention of Resistance to Levofloxacin and Ciprofloxacin in Streptococcus pneumoniae

Por Louie, Arnold, Brown, David L., Liu, Weiguo, Kulawy, Robert W., Deziel, Mark R., Drusano, George L.
Publicado em 2007

Anidulafungin Pharmacokinetics and Microbial Response in Neutropenic Mice with Disseminated Candidiasis

Por Gumbo, Tawanda , Drusano, George L., Liu, Weiguo, Ma, Lei, Deziel, Mark R., Drusano, Michael F. , Louie, Arnold
Publicado em 2006

Concentration-Dependent Mycobacterium tuberculosis Killing and Prevention of Resistance by Rifampin

Por Gumbo, Tawanda, Louie, Arnold, Deziel, Mark R., Liu, Weiguo, Parsons, Linda M., Salfinger, Max, Drusano, George L.
Publicado em 2007

Quinolone Efflux Pumps Play a Central Role in Emergence of Fluoroquinolone Resistance in Streptococcus pneumoniae

Por Jumbe, Nelson L., Louie, Arnold, Miller, Michael H., Liu, Weiguo, Deziel, Mark R., Tam, Vincent H., Bachhawat, Reetu, Drusano, George L.
Publicado em 2006

Effective Antimicrobial Regimens for Use in Humans for Therapy of Bacillus anthracis Infections and Postexposure Prophylaxis

Por Deziel, Mark R., Heine, Henry, Louie, Arnold, Kao, Mark, Byrne, William R., Basset, Jennifer, Miller, Lynda, Bush, Karen, Kelly, Michael, Drusano, G. L.
Publicado em 2005

Application of a mathematical model to prevent in vivo amplification of antibiotic-resistant bacterial populations during therapy

Por Jumbe, Nelson, Louie, Arnold, Leary, Robert, Liu, Weiguo, Deziel, Mark R., Tam, Vincent H., Bachhawat, Reetu, Freeman, Christopher, Kahn, James B., Bush, Karen, Dudley, Michael N., Miller, Michael H., Drusano, George L.
Publicado em 2003